Evidence map›Paper›PMID 31256146›Full record

ArticleJournal of Huntington's disease2019

A Feasibility Study of Quantitative Motor Assessments in Children Using the Q-Motor Suite.

Ellen van der Plas, Robin Schubert, Ralf Reilmann, Peggy C Nopoulos

Open access · greenAbstract read
In one paragraph

Article in Journal of Huntington's disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Ellen van der PlasDepartment of Psychiatry, University of Iowa Hospital and Clinics, Iowa City, IA, USA.
Robin SchubertGeorge Huntington Institute, Muenster, Germany.
Ralf ReilmannGeorge Huntington Institute, Muenster, Germany.
Peggy C NopoulosDepartment of Psychiatry, University of Iowa Hospital and Clinics, Iowa City, IA, USA.
University of Iowa Hospitals and Clinics · USGeorge Huntington Institute · DEUniversity of Münster · DE

Funding

Longitudinal Assessment of Brain Structure and Function in Juvenile Onset Huntington's DiseaseU01NS055903 · NINDS · UNIVERSITY OF IOWA · PI NOPOULOS, PEGGY C · 2019 to 2025
$17.4M
NINDS NIH HHS U01 NS055903
6 · The paper itself

Abstract

Q-Motor is utilized across various clinical trials in adults with Huntington's disease (HD) to provide quantitative, reliable assessments of motor abilities. With gene-knockdown therapies entering the clinic, development of preventative therapies for pediatric carriers of the HD mutation seems imminent. It is currently unclear if Q-Motor is useful for tracking changes in motor abilities in pediatric HD patients or at-risk youth, as most assessments have never been administered in children. We demonstrate the feasibility of administering Q-Motor tasks in a sample of children recruited from the community, and we show that Q-Motor is sensitive to age-related changes in motor abilities.

Indexed as

Motor ActivityAdolescentChildFeasibility StudiesFemaleHumansHuntington DiseaseMaleNeuropsychological TestsadolescentschildrendevelopmentendpointHuntington’s diseasemotorQ-Motor

Identifiers

PMID31256146
PMCPMC7410091
OpenAlexW2954074769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.