ArticleThe Journal of the Acoustical Society of America2019
Sex differences in hearing: Probing the role of estrogen signaling.
Article in The Journal of the Acoustical Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 113 citations in OpenAlex.
- Association of Menopause and Hormone Replacement Therapy with Hearing Loss.The Annals of otology, rhinology, and laryngology · 2026Article
- Genotype-guided Recall Delineates the Adult Auditory Phenotype in GJB2 p.V37I Homozygotes: High-frequency Vulnerability and Environmental Modulation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Neuroprotective potential of a TrkB-FL-derived cell-penetrating peptide in cochlear synaptopathy and noise-induced hearing loss.Molecular medicine (Cambridge, Mass.) · 2026Article
- Cochlear histopathology in macaques after noise-induced temporary threshold shifts.Hearing research · 2026Article
- Identification of sensorineural hearing loss subtypes using unsupervised machine learning and assessment of their replicability.Scientific reports · 2026Article
- Effects of Curcumin in Workers with Noise-Induced Hearing Loss: Preliminary Report.Iranian journal of otorhinolaryngology · 2026Article
- Time-Series Transcriptome Analysis of the Older Adult Mouse Cochlea After Noise-Induced Hearing Loss Reveals an Acute Immune Response and Recovery-Associated Pathways.Molecular neurobiology · 2025Article
- Sex differences in response to kanamycin-induced ototoxicity in C57BL/6 J mice.Scientific reports · 2025Article
- Gender differences in self-reported hearing loss and hearing aid use: a cross-national comparison.BMJ global health · 2025Article
- Optical coherence tomography imaging demonstrates endolymphatic hydrops in the lateral and posterior semicircular canals in noise-exposed mice.Hearing research · 2025Article
- A review of occupational noise-induced hearing loss: focus on mechanisms and preventive measures.British medical bulletin · 2025Review
- Cognitive-and lifestyle-related microstructural variation in the ageing human hippocampus.Brain structure & function · 2025Article
- The association between occupational noise exposure and hearing loss among petrochemical enterprise workers in Hainan, South China.Scientific reports · 2025Article
- Educational Disparities in Age-Related Hearing Loss and Hearing Aid Use Across Age, Gender, and European Region.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Establishing a robust triangulation framework to explore the relationship between hearing loss and Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Pathophysiological insights and therapeutic developments in age-related hearing loss: a narrative review.Frontiers in aging neuroscience · 2025Review
- Muscle quality correlates with hearing thresholds: a cross-sectional analysis.Frontiers in aging · 2025Article
- An Analysis of Hearing Status and Hearing Healthcare Utilization of English-Speaking Expatriates in Thailand.Audiology & neuro-otology · 2025Article
- A descriptive epidemiological study of the prevalence of self-reported sensory difficulties by age group, sex, education, disability, and migration status in Sweden in 2020.BMC public health · 2024Article
- The curvature quantification of wave I in auditory brainstem responses detects cochlear synaptopathy in human beings.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Hearing loss is the most common form of sensory impairment in humans, with an anticipated rise in incidence as the result of recreational noise exposures. Hearing loss is also the second most common health issue afflicting military veterans. Currently, there are no approved therapeutics to treat sensorineural hearing loss in humans. While hearing loss affects both men and women, sexual dimorphism is documented with respect to peripheral and central auditory physiology, as well as susceptibility to age-related and noise-induced hearing loss. Physiological differences between the sexes are often hormone-driven, and an increasing body of literature demonstrates that the hormone estrogen and its related signaling pathways may in part, modulate the aforementioned differences in hearing. From a mechanistic perspective, understanding the underpinnings of the hormonal modulation of hearing may lead to the development of therapeutics for age related and noise induced hearing loss. Here the authors review a number of studies that range from human populations to animal models, which have begun to provide a framework for understanding the functional role of estrogen signaling in hearing, particularly in normal and aberrant peripheral auditory physiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.