Evidence map›Paper›PMID 31254136›Full record

ReviewJournal of muscle research and cell motility2019

Emerging regulators of vascular smooth muscle cell migration.

TecLino Afewerki, Sultan Ahmed, Derek Warren

Abstract readReview
In one paragraph

Review in Journal of muscle research and cell motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Direct active Fyn-paxillin interaction regulates vascular smooth muscle cell migration.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2023
    Review
  6. Article
  7. Long non-coding RNAAnnals of translational medicine · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

TecLino AfewerkiSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
Sultan AhmedSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
Derek WarrenSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. derek.warren@uea.ac.uk.

Funding

British Heart Foundation FS/17/32/32916British Heart Foundation FS/18/35/33681
6 · The paper itself

Abstract

Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall and normally adopt a quiescent, contractile phenotype. VSMC migration is tightly controlled, however, disease associated changes in the soluble and insoluble environment promote VSMC migration. Classically, studies investigating VSMC migration have described the influence of soluble factors. Emerging data has highlighted the importance of insoluble factors, including extracellular matrix stiffness and porosity. In this review, we will recap on the important signalling pathways that regulate VSMC migration and reflect on the potential importance of emerging regulators of VSMC function.

Indexed as

Cell MovementAnimalsExtracellular MatrixHumansMuscle, Smooth, VascularMyocytes, Smooth MuscleMechanotransductionMigrationSignallingVascular smooth muscle cell

Identifiers

PMID31254136
PMCPMC6726670

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.