Evidence map›Paper›PMID 31253755›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling.

Salim Megat, Pradipta R Ray, Diana Tavares-Ferreira, Jamie K Moy, Ishwarya Sankaranarayanan, Andi Wanghzou, Tzu Fang Lou, Paulino Barragan-Iglesias, Zachary T Campbell, Gregory Dussor and 1 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 124 citations in OpenAlex.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Salim MegatSchool of Behavioral and Brain Sciences.ORCID 0000-0003-2186-6770
Pradipta R RaySchool of Behavioral and Brain Sciences.
Diana Tavares-FerreiraSchool of Behavioral and Brain Sciences.
Jamie K MoySchool of Behavioral and Brain Sciences.
Ishwarya SankaranarayananSchool of Behavioral and Brain Sciences.ORCID 0000-0002-6765-0281
Andi WanghzouSchool of Behavioral and Brain Sciences.
Tzu Fang LouDepartment of Biological Sciences, University of Texas at Dallas, Richardson, Texas, 75080.
Paulino Barragan-IglesiasSchool of Behavioral and Brain Sciences.ORCID 0000-0003-3178-8606
Zachary T CampbellCenter for Advanced Pain Studies, and.ORCID 0000-0002-3768-6996
Gregory DussorSchool of Behavioral and Brain Sciences.ORCID 0000-0002-1193-9238
Theodore J PriceSchool of Behavioral and Brain Sciences, Theodore.price@utdallas.edu.ORCID 0000-0002-6971-6221
Carolinas Center for Advanced Management of Pain · USThe University of Texas at Dallas · USCenter for Behavioral Brain Sciences · DE

Funding

Translation Control of Pain PlasticityR01NS065926 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI PRICE, THEODORE J. · 2010 to 2023
$5.7M
Protease Activated Receptor Type 2 Targeting for Migraine PainR01NS098826 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI GREGORY O DUSSOR, Theodore J Price · 2017 to 2026
$3.4M
Training in Mechanisms and Clinical Presentation of PainT32NS073548 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jami Lynn Saloman, BRADLEY K. TAYLOR · 2012 to 2026
$3.1M
Sex-specific regulation of local translation and chronic pain mechanisms in femalesR01NS102161 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI AKOPIAN, ARMEN N, PRICE, THEODORE J. · 2018 to 2022
$2.5M
3’ End Regulation in Nociceptor PlasticityR01NS100788 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI CAMPBELL, ZACHARY · 2017 to 2021
$2.0M
NINDS NIH HHS R01 NS065926NINDS NIH HHS R01 NS098826NINDS NIH HHS R01 NS100788NINDS NIH HHS R01 NS102161NINDS NIH HHS T32 NS073548
6 · The paper itself

Abstract

Nociceptors located in the trigeminal ganglion (TG) and DRG are the primary sensors of damaging or potentially damaging stimuli for the head and body, respectively, and are key drivers of chronic pain states. While nociceptors in these two tissues show a high degree of functional similarity, there are important differences in their development lineages, their functional connections to the CNS, and recent genome-wide analyses of gene expression suggest that they possess some unique genomic signatures. Here, we used translating ribosome affinity purification to comprehensively characterize and compare mRNA translation in

Indexed as

TranscriptomeAnimalsFemaleGanglia, SpinalGene Expression ProfilingMaleMiceNeuronsNociceptorsSignal TransductionTrigeminal GanglionDRGmTORneuropathic painTGTRAP

Identifiers

PMID31253755
PMCPMC6733558
OpenAlexW2954606077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.