ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
In a Temporally Segmented Experience Hippocampal Neurons Represent Temporally Drifting Context But Not Discrete Segments.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis.Cognition · 2026Article
- Adaptation of hippocampal spatial and contextual representations to task structure.Science advances · 2025Article
- The influence of emotion on temporal context models.Cognition & emotion · 2025Review
- Time-scale invariant contingency yields one-shot reinforcement learning despite extremely long delays to reinforcement.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Effects of social context manipulation on dorsal and ventral hippocampal neuronal responses.Hippocampus · 2023Article
- The neural bases for timing of durations.Nature reviews. Neuroscience · 2022Review
- Contingent Amygdala Inputs Trigger Heterosynaptic LTP at Hippocampus-To-Accumbens Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- The limited reach of surprise: Evidence against effects of surprise on memory for preceding elements of an event.Psychonomic bulletin & review · 2022Article
- Medial prefrontal cortex and hippocampal activity differentially contribute to ordinal and temporal context retrieval during sequence memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2021Article
- Preexisting hippocampal network dynamics constrain optogenetically induced place fields.Neuron · 2021Article
- Review
- Multi-level analyses of associative recognition memory: the whole is greater than the sum of its parts.Current opinion in behavioral sciences · 2020Review
- Semantic Knowledge Representation for Strategic Interactions in Dynamic Situations.Frontiers in neurorobotics · 2020Article
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Authors and funding
4 authors.
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Abstract
There is widespread agreement that episodic memory is organized into a timeline of past experiences. Recent work suggests that the hippocampus may parse the flow of experience into discrete episodes separated by event boundaries. A complementary body of work suggests that context changes gradually as experience unfolds. We recorded from hippocampal neurons as male Long-Evans rats performed 6 blocks of an object discrimination task in sets of 15 trials. Each block was separated by removal from the testing chamber for a delay to enable segmentation. The reward contingency reversed from one block to the next to incentivize segmentation. We expected animals to hold two distinct, recurring representations of context to match the two distinct rule contingencies. Instead, we found that overtrained rats began each block neither above nor below chance but by guessing randomly. While many units had clear firing fields selective to the conjunction of objects in places, a significant population also reflected a continuously drifting code both within block and across blocks. Despite clear boundaries between blocks, we saw no neural evidence for event segmentation in this experiment. Rather, the hippocampal ensemble drifted continuously across time. This continuous drift in the neural representation was consistent with the lack of segmentation observed in behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.