Evidence map›Paper›PMID 31253655›Full record

ArticleLife science alliance2019

Dietary restriction induces posttranscriptional regulation of longevity genes.

Jarod A Rollins, Dan Shaffer, Santina S Snow, Pankaj Kapahi, Aric N Rogers

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

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  6. Modified tau leads to neuronal and global ribosome dysfunction inbioRxiv : the preprint server for biology · 2025
    Article
  7. Systematic identification of exercise-induced anti-aging processes involving intron retention.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jarod A RollinsMount Desert Island Biological Laboratory, Salisbury Cove, ME, USA jrollins@mdibl.org.ORCID 0000-0002-6279-7831
Dan ShafferMount Desert Island Biological Laboratory, Salisbury Cove, ME, USA.
Santina S SnowMount Desert Island Biological Laboratory, Salisbury Cove, ME, USA.
Pankaj KapahiBuck Institute for Research on Aging, Novato, CA, USA.
Aric N RogersMount Desert Island Biological Laboratory, Salisbury Cove, ME, USA arogers@mdibl.org.ORCID 0000-0002-6149-6842
Mount Desert Island Biological Laboratory · USBuck Institute for Research on Aging · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Understanding the role of thyroid hormone signaling during axolotl limb regenerationP20GM104318 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2013 to 2023
$23.0M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Lifespan extension by differential translation mediated by eIF-4G in C. elegansR00AG037621 · NIA · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI ROGERS, ARIC N · 2013 to 2015
$739k
Nonsense mediated decay and alternative splicing in lifespan extension from dietary restriction in C. elegans.R21AG056743 · NIA · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI ROGERS, ARIC N · 2017 to 2018
$446k
NIA NIH HHS R00 AG037621NIA NIH HHS R21 AG056743NIGMS NIH HHS P20 GM103423NIGMS NIH HHS P20 GM104318NIH HHS P40 OD010440
6 · The paper itself

Abstract

Dietary restriction (DR) increases life span through adaptive changes in gene expression. To understand more about these changes, we analyzed the transcriptome and translatome of

Indexed as

Caloric Restriction3' Untranslated Regions5' Untranslated RegionsAlternative SplicingAmino AcidsAnimalsCaenorhabditis elegansCarrier ProteinsEndoribonucleasesGene Expression RegulationIntronsLongevityMicroRNAsMuscle ProteinsNeuropeptidesProtein Biosynthesis3' Untranslated Regions5' Untranslated RegionsAmino AcidsCarrier ProteinsEndoribonucleasesMicroRNAsMuscle ProteinsNeuropeptidesRNA, MessengerSMG6 protein, humanSMG7 protein, humanTelomerase

Identifiers

PMID31253655
PMCPMC6600014
OpenAlexW2955977336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.