Evidence map›Paper›PMID 31253624›Full record

ArticleBMJ open2019

Carrier prevalence and risk factors for colonisation of multiresistant bacteria in Danish emergency departments: a cross-sectional survey.

Helene Skjøt-Arkil, Christian Backer Mogensen, Annmarie Touborg Lassen, Isik S Johansen, Ming Chen, Poul Petersen, Karen V Andersen, Svend Ellermann-Eriksen, Jørn M Møller, Marc Ludwig and 5 more

4 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03352167 completednot on this map

Antibiotic Resistance in Danish Emergency Departments. Prevalence, Risk Factors and Definition of Risk Groups.

Typeobservational_patient_registrySponsorUniversity of Southern DenmarkRan2018 to 2018Enrolled5,117ConditionsAntibiotic Resistance, Bacterial
NCT04595526 nacompletednot on this mapstarted 2020, after this paper: background citation

Optimal Collection of Specimens of the Lower Respiratory Tract

TypeinterventionalSponsorUniversity of Southern DenmarkRan2020 to 2021Enrolled280ConditionsRespiratory Tract InfectionsArmsForced expiratory technique and induced sputum, Tracheal suction
NCT04651712 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect of a Point-of-care Sputum Specimen Assay on Antibiotic Treatment of Patients Admitted Acutely With Suspected Pneumonia: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Southern DenmarkRan2021 to 2022Enrolled290ConditionsPneumonia, BacterialArmsPOC-PCR
NCT04661085 completednot on this mapstarted 2021, after this paper: background citation

A Descriptive Study of Patients Suspected With Infection in the Emergency Department, With a Special Focus on Infection With Unknown Origin.

TypeobservationalSponsorUniversity of Southern DenmarkRan2021 to 2022Enrolled966ConditionsInfectionArmsBroader Medical history and clinical tests
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Vancomycin-resistant Enterococcus faecium: should we screen on admission?APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Travel-Related Antimicrobial Resistance: A Systematic Review.Tropical medicine and infectious disease · 2021
    Review
  12. Article
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Helene Skjøt-ArkilDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-2236-6375
Christian Backer MogensenDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-8254-089X
Annmarie Touborg LassenDepartment of Emergency Medicine, Odense University Hospital, Odense, Denmark.
Isik S JohansenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Ming ChenDepartment of Clinical Microbiology, Hospital Sønderjylland, Soenderborg, Denmark.
Poul PetersenRegional Hospital West Jutland, Herning, Denmark.
Karen V AndersenEmergency Department, Aarhus University Hospital, Aarhus, Denmark.
Svend Ellermann-EriksenDepartment of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
Jørn M MøllerEmergency Department, Aalborg University Hospital, Aalborg, Denmark.
Marc LudwigEmergency Department, North Denmark Regional Hospital, Hjørring, Denmark.
David Fuglsang-DamgaardDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.
Finn Erland NielsenEmergency Department, Slagelse Sygehus, Slagelse, Denmark.
Dan B PetersenEmergency Department, Zealand University Hospital, Køge, Denmark.
Ulrich S JensenDepartment of Clinical Microbiology, Slagelse Sygehus, Slagelse, Denmark.
Flemming S RosenvingeDepartment of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
Odense University Hospital · DKAalborg University Hospital · DKAarhus University Hospital · DKSlagelse Hospital · DKUniversity of Southern Denmark · DKNorth Denmark Region · DKRegional Hospital West Jutland · DKSygehus Sønderjylland · DKZealand University Hospital Køge · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to describe the carrier prevalence and demographic variation of four different multiresistant bacteria (MRB) among acute patients in Danish emergency departments (EDs): methicillin-resistant

designMulticentre descriptive and analytic cross-sectional survey.

settingEight EDs and four clinical microbiology departments in Denmark.

participantsAdults visiting the ED.

main outcome measuresSwabs from nose, throat and rectum were collected and analysed for MRSA, ESBL, VRE and CPE. The primary outcome was the prevalence of MRB carriage, and secondary outcomes relation to risk factors among ED patients.

resultsWe included 5117 patients in the study. Median age was 68 years (54-77) and gender was equally distributed. In total, 266 (5.2%, 95% CI 4.6 to 5.8) were colonised with at least one MRB. No significant difference was observed between male and female patients, between age groups and between university and regional hospitals. Only 5 of the 266 patients with MRB were colonised with two of the included bacteria and none with more than two. CPE prevalence was 0.1% (95% CI 0.0 to 0.2), MRSA prevalence was 0.3% (95% CI 0.2 to 0.5), VRE prevalence was 0.4% (95% CI 0.3 to 0.6) and ESBL prevalence was 4.5% (95% CI 3.9 to 5.1). Risk factors for MRB carriage were previous antibiotic treatment, previous hospital stay, having chronic respiratory infections, use of urinary catheter and travel to Asia, Oceania or Africa.

conclusionEvery 20th patient arriving to a Danish ED brings MRB to the hospital. ESBL is the most common MRB in the ED. The main risk factors for MRB carriage are recent antibiotic use and travel abroad. TRIAL REGISTRATION NUMBER: NCT03352167;Post-results.

Indexed as

Carrier StateDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsStaphylococcal InfectionsStreptococcal InfectionsAgedAnti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeCross-Sectional StudiesDenmarkEmergency Service, HospitalFemaleHumansInfection ControlMaleMethicillin-Resistant Staphylococcus aureusAnti-Bacterial Agentscarbapenemase-producing enterobacteriacarrier prevalenceextended-spectrum beta-lactamase-producing enterobacteriamethicillin resistant staphylococcus aureusrisk factorsvancomycin resistant enterococci

Identifiers

PMID31253624
PMCPMC6609076
OpenAlexW2954027031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.