ArticleJournal of cardiothoracic surgery2019
Long-term outcome after mitral valve replacement using biological versus mechanical valves.
Article in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mechanical or biologic prostheses for mitral valve replacement: A systematic review and meta-analysis.Clinical cardiology · 2022Pooled it
- The choice of mitral valve surgery type and mid-term outcomes in patients up to 70 years of age: Results of the AUTHEARTVISIT study.JTCVS open · 2026Article
- Mid-term outcomes and hemodynamic performances of Abbott Epic mitral bioprosthesis: a single-center study.General thoracic and cardiovascular surgery · 2026Article
- Association of Renal Impairment Severity with Surgical Outcomes in Patients with Infective Endocarditis.Current cardiology reviews · 2026Article
- Comparison of a novel mechanical valve versus stented bioprosthetic valves for isolated mitral valve replacement in patients older than 65 years.JTCVS open · 2025Article
- Effect of Systemic Immune-Inflammation Index on Prognosis in Non-Functional Mitral Regurgitation Patients Undergoing Isolated Mitral Valve Replacement.Brazilian journal of cardiovascular surgery · 2025Article
- Mechanistic Insights into Bioprosthetic Heart Valve Calcification and Anti-Calcification Strategies.Reviews in cardiovascular medicine · 2025Review
- Article
- Cardiac CT in Large Vessel Occlusion Stroke for the Evaluation of Non-Thrombotic and Non-Atrial-Fibrillation-Related Embolic Causes.Neurology international · 2025Article
- Temporal changes in characteristics, incidence, and mortality in patients undergoing surgical intervention for mitral stenosis.Scientific reports · 2024Article
- Long-term outcomes of isolated mechanical versus bioprosthetic mitral valve replacement in different age groups of propensity-matched patients.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Observational
- Nurses' knowledge, attitudes, and practices about rehabilitation of patients after heart valve surgery in Namibia.Health SA = SA Gesondheid · 2024Article
- Long-Term Outcomes Stratified by Age in Patients with a Mechanical versus Biological Mitral Valve Replacement.Journal of cardiovascular development and disease · 2022Article
- Surgical Aortic Mitral Curtain Replacement: Systematic Review and Metanalysis of Early and Long-Term Results.Journal of clinical medicine · 2021Review
- Long-term results of endoclamping in patients undergoing minimally invasive mitral valve surgery where external aortic clamping cannot be used - a propensity matched analysis.Journal of cardiothoracic surgery · 2020Article
- Long-term outcomes of concomitant tricuspid valve repair in patients undergoing mitral valve surgery.Journal of cardiothoracic surgery · 2020Article
- Endomyocardial fibrosis.Cardiovascular diagnosis and therapy · 2020Article
Corrections and comments
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8 authors.
Funding
Abstract
backgroundThis study compared long-term outcomes of biological and mechanical mitral valve replacement (MVR) in patients requiring replacement of the mitral valve where repair was not feasible.
methodsA single-centre registry of patients receiving MVR between 2005 and 2015 was established. Thirty-day mortality and long-term outcomes were analysed and compared.
resultsThree hundred twenty four patients underwent MVR (265 biological; 59 mechanical valves). Patients receiving biological valves were older (p < 0.001), had a higher log EuroSCORE (p < 0.001) and received less minimally invasive surgery (p < 0.001). Immediate procedural mortality was 1.9%, which only occurred in the biological valve group. At 30 days, 9.0% of patients had died, 4.0% experienced stroke, 8.0% received a pacemaker and 10.5% suffered an acute renal failure. The rate of re-thoracotomy (14.2%) was lower in the biological (12.5%) than in the mechanical valve group (22.0%; adjOR 0.45 [0.20-1.00]; p = 0.050). Frequent long-term complications were stroke (9.2%) and bleeding (4.8%), with bleeding complications being higher in the mechanical valve group (p = 0.009). During the follow-up period biological valves showed a numerically higher survival rate during the first years, which shifted after 3 years in favour of mechanical valves. At 10 years, survival rates were 62.4% vs. 77.1% in the biological and mechanical valve groups (p = 0.769). Hazard ratio after adjustment was 0.833 (95% CI 0.430-1.615).
conclusionThese data confirm that mechanical valve implantation is associated with an increased risk of bleeding. While there was a potential survival benefit during the first years after surgery for patients receiving a biological valves the difference became insignificant after a follow-up of 10 years.
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