Evidence map›Paper›PMID 31253093›Full record

ArticleBMC genomics2019

miRkwood: a tool for the reliable identification of microRNAs in plant genomes.

Isabelle Guigon, Sylvain Legrand, Jean-Frédéric Berthelot, Sébastien Bini, Delphine Lanselle, Mohcen Benmounah, Hélène Touzet

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. miRNA408 fromBiomolecules · 2025
    Article
  2. Review
  3. Detection of Ethylene Signaling Using Bioinformatics Tools in Plants.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Potential role of the regulatoryFrontiers in plant science · 2023
    Article
  5. Exploitation of epigenetic variation of crop wild relatives for crop improvement and agrobiodiversity preservation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Review
  6. Article
  7. The Multiverse of Plant Small RNAs: How Can We Explore It?International journal of molecular sciences · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Isabelle GuigonUniversity of Lille - bilille, F-59000, Lille, France.
Sylvain LegrandUniversity of Lille, CNRS, UMR 8198 - Evo-Eco-Paleo, F-59000, Lille, France. sylvain.legrand@univ-lille.fr.ORCID http://orcid.org/0000-0002-7098-0273
Jean-Frédéric BerthelotUniversity of Lille - bilille, F-59000, Lille, France.
Sébastien BiniUniversity of Lille, CNRS, INRIA, UMR 9189 - CRIStAL, F-59000, Lille, France.
Delphine LanselleUniversity of Lille, CNRS, UMR 8198 - Evo-Eco-Paleo, F-59000, Lille, France.
Mohcen BenmounahUniversity of Lille - bilille, F-59000, Lille, France.
Hélène TouzetUniversity of Lille, CNRS, INRIA, UMR 9189 - CRIStAL, F-59000, Lille, France. helene.touzet@univ-lille.fr.
Centre National de la Recherche Scientifique · FRUniversité de Lille · FR

Funding

Agence Nationale de la recherche, France 10-INBS-0009Ministère de l'Enseignement Supérieur et de la Recherche, France CPER Climibio
6 · The paper itself

Abstract

backgroundMicroRNAs (miRNAs) play crucial roles in post-transcriptional regulation of eukaryotic gene expression and are involved in many aspects of plant development. Although several prediction tools are available for metazoan genomes, the number of tools dedicated to plants is relatively limited.

resultsHere, we present miRkwood, a user-friendly tool for the identification of miRNAs in plant genomes using small RNA sequencing data. Deep-sequencing data of Argonaute associated small RNAs showed that miRkwood is able to identify a large diversity of plant miRNAs and limits false positive predictions. Moreover, it outperforms current tools such as ShortStack and contrary to ShortStack, miRkwood provides a quality score allowing users to rank miRNA predictions.

conclusionmiRkwood is a very efficient tool for the annotation of miRNAs in plant genomes. It is available as a web server, as a standalone version, as a docker image and as a Galaxy tool: http://bioinfo.cristal.univ-lille.fr/mirkwood.

Indexed as

SoftwareBase SequenceGenome, PlantGenomicsInverted Repeat SequencesMicroRNAsThermodynamicsMicroRNAsAGO-IPMicro-RNAsPlant genomeSmall RNA-seq

Identifiers

PMID31253093
PMCPMC6599362
OpenAlexW2955964491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.