Evidence map›Paper›PMID 31253086›Full record

Trial reportBMC anesthesiology2019

Continuous Adductor Canal Block used for postoperative pain relief after medial Unicondylar Knee Arthroplasty: a randomized, double-blind, placebo-controlled trial.

Fei Lan, Yanyan Shen, Yanhui Ma, Guanglei Cao, Nicole Philips, Ting Zhang, Tianlong Wang

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
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  3. Review
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  5. Review
  6. Article
  7. [Research progress on analgesic effect of adductor canal block after knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fei LanDepartment of Anesthesiology Xuanwu Hospital, Capital Medical University, No.45, Changchun Street, Beijing, 100053, China.
Yanyan ShenDepartment of Anesthesiology, Peking University International Hospital, Beijing, China.
Yanhui MaDepartment of Anesthesiology Xuanwu Hospital, Capital Medical University, No.45, Changchun Street, Beijing, 100053, China.
Guanglei CaoDepartment of Orthopedics Xuanwu Hospital, Capital Medical University, Beijing, China.
Nicole PhilipsDepartment of Critical Care Medicine St. Michael's Hospital, University of Toronto, Toronto, Canada.
Ting ZhangDepartment of Anesthesiology Xuanwu Hospital, Capital Medical University, No.45, Changchun Street, Beijing, 100053, China.
Tianlong WangDepartment of Anesthesiology Xuanwu Hospital, Capital Medical University, No.45, Changchun Street, Beijing, 100053, China. w_tl5595@hotmail.com.ORCID 0000-0001-6291-2505
Capital Medical University · CNPeking University · CNSt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripheral nerve block and local infiltration analgesia (LIA) provide good analgesia after knee replacement. This study evaluated the additional analgesic efficacy of continuous adductor canal block (ACB) added to single-dose LIA after medial unicondylar knee arthroplasty (UKA). We hypothesized ACB would lower pain scores and facilitate postoperative ambulation.

methodsForty-six patients were enrolled into this double-blind, randomized, placebo-controlled trial. UKA was performed and all patients received single-dose LIA intraoperatively. Patients were randomized into two groups: Group RP receiving 0.2% ropivacaine or Group Con receiving normal saline. A flow at 6 mL/h was administered for 48 h through a catheter in the adductor canal. Primary outcome was movement pain score at 24 h using the numeric rating scale (NRS-11). Secondary outcomes included serial postoperative pain scores, rate of patients with NRS>3 at rest and movement within 24 and 48 h postoperatively, time to breakthrough pain, quadriceps motor strength, ambulated distance, catheter related infection and patient satisfaction.

resultsForty-two patients were analyzed. Pain scores with movement at 24 h postoperatively were significantly lower in Group RP than that in Group Con (3 vs. 5 NRS, P<0.001). Compared with Group Con, breakthrough pain occurred later in Group RP (18.5 vs 10.0 h, P = 0.002), serial pain scores at rest and with movement and rate of patients with NRS>3 with movement after surgery were significantly lower. Quadriceps motor strength was equivalent, however, ambulated distance on postoperative day 1 and 2 in Group Con was significant less (19.7 vs 37.3 m, P = 0.046; 33.4 vs 59.5 m, P = 0.002).

conclusionsContinuous adductor canal block added to single-dose LIA offered better analgesia and facilitated ambulation without motor weakness after medial UKA.

trial registrationClinical Trial Registration: ChiCTR-IOR-16008720 ; Registered 25 June 2016.

Indexed as

AgedAnesthetics, LocalArthroplasty, Replacement, KneeDouble-Blind MethodFemaleHumansMaleMiddle AgedNerve BlockPain MeasurementPatient SatisfactionPostoperative PainQuadriceps MuscleRopivacaineWalkingAnesthetics, LocalRopivacaineAdductor canal blockAnalgesiaArthroplastyKneeLocal

Identifiers

PMID31253086
PMCPMC6599333
OpenAlexW2955669708

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.