Evidence map›Paper›PMID 31252692›Full record

ArticleInternational journal of molecular sciences2019

Marek's Disease Virus Infection Induced Mitochondria Changes in Chickens.

Qin Chu, Yi Ding, Wentao Cai, Lei Liu, Huanmin Zhang, Jiuzhou Song

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Qin ChuInstitute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100094, China.
Yi DingDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20740, USA.
Wentao CaiDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20740, USA.
Lei LiuDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20740, USA.
Huanmin ZhangUSDA, Agriculture Research Service, Avian Disease and Oncology Laboratory, East Lansing, MI 48823, USA.ORCID 0000-0003-4896-2391
Jiuzhou SongDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD 20740, USA. songj88@umd.edu.
University of Maryland, College Park · USBeijing Academy of Agricultural and Forestry Sciences · CNMichigan Department of Agriculture and Rural Development · US

Funding

China Scholarship Council (CSC) 2017U.S. Department of Agriculture (USDA)-Nation Research Initiative/National Institute of Food and Agriculture (NRI/NIFA) 2011-67015-30183
6 · The paper itself

Abstract

Mitochondria are crucial cellular organelles in eukaryotes and participate in many cell processes including immune response, growth development, and tumorigenesis. Marek's disease (MD), caused by an avian alpha-herpesvirus Marek's disease virus (MDV), is characterized with lymphomas and immunosuppression. In this research, we hypothesize that mitochondria may play roles in response to MDV infection. To test it, mitochondrial DNA (mtDNA) abundance and gene expression in immune organs were examined in two well-defined and highly inbred lines of chickens, the MD-susceptible line 7

Indexed as

AnimalsAvian ProteinsChickensDisease ResistanceDNA-Directed DNA PolymeraseDNA, MitochondrialMarek DiseaseMitochondriaMitochondrial ProteinsSpleenUp-RegulationAvian ProteinsDNA-Directed DNA PolymeraseDNA, MitochondrialMitochondrial Proteinsgene expressionimmune responseMarek’s disease virusmitochondrial DNA copy numberT cell transformation

Identifiers

PMID31252692
PMCPMC6651546
OpenAlexW2955567483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.