Evidence map›Paper›PMID 31252662›Full record

ReviewMolecules (Basel, Switzerland)2019

A Novel Drug Design Strategy: An Inspiration from Encaging Tumor by Metallofullerenol Gd@C

Jinxia Li, Linlin Chen, Liang Yan, Zhanjun Gu, Zhaofang Chen, Aiping Zhang, Feng Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Rare Earths-The Answer to Everything.Molecules (Basel, Switzerland) · 2024
    Review
  2. Article
  3. Review
  4. Effects of Aqueous Dispersions of CInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jinxia LiCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.
Linlin ChenCollege of Pharmacy, Shanxi Medical University, Taiyuan 030001, China.
Liang YanCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.
Zhanjun GuCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.
Zhaofang ChenJiangsu Key Laboratory of Hazardous Chemicals Safety and Control, College of Safety Science and Engineering, Nanjing Tech University, Nanjing 210009, China.
Aiping ZhangCollege of Pharmacy, Shanxi Medical University, Taiyuan 030001, China.
Feng ZhaoCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China. zhaof@ihep.ac.cn.ORCID 0000-0001-8567-7501
Chinese Academy of Sciences · CNShanxi Medical University · CNNanjing Tech University · CN

Funding

National Natural Science Foundation of China 21301176, 11305182
6 · The paper itself

Abstract

Cancer remains a major threat to human health worldwide. Cytotoxicity has imposed restrictions on the conventional cytotoxic drug-based chemotherapy. The rapidly-developing nanomedicine has shown great promise in revolutionizing chemotherapy with improved efficiency and reduced toxicity. Gd@C

Indexed as

Antineoplastic AgentsCell Line, TumorDrug DesignFullerenesGadoliniumHumansMolecular Dynamics SimulationNanomedicineNanoparticlesAntineoplastic AgentsFullerenesGadoliniumdrug designencaging tumorGd@C82(OH)22key and lock principlemetallofullerenol

Identifiers

PMID31252662
PMCPMC6650816
OpenAlexW2955850210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.