Evidence map›Paper›PMID 31252593›Full record

ArticleJournal of clinical medicine2019

Use of Antiplatelet Agents and Survival of Tuberculosis Patients: A Population-Based Cohort Study.

Meng-Rui Lee, Ming-Chia Lee, Chia-Hao Chang, Chia-Jung Liu, Lih-Yu Chang, Jun-Fu Zhang, Jann-Yuan Wang, Chih-Hsin Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. The "yeast-drop" treatment protocol in theFrontiers in tuberculosis · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Meng-Rui LeeDepartment of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu 30059, Taiwan.ORCID 0000-0002-7220-4833
Ming-Chia LeeDepartment of Pharmacy, New Taipei City Hospital, New Taipei City 24141, Taiwan.ORCID 0000-0002-6209-2313
Chia-Hao ChangDepartment of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu 30059, Taiwan.
Chia-Jung LiuDepartment of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu 30059, Taiwan.
Lih-Yu ChangDepartment of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu 30059, Taiwan.
Jun-Fu ZhangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 10002, Taiwan.
Jann-Yuan WangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 10002, Taiwan.ORCID 0000-0003-3406-366X
Chih-Hsin LeeDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. chleetw@tmu.edu.tw.ORCID 0000-0003-1492-3044
National Taiwan University Hospital · TWNational Taiwan University · TWWan Fang Hospital · TW

Funding

Ministry of Health and Welfare MOHW105-CDC-C-114-00103Ministry of Health and Welfare MOHW106-CDC-C-11400104Ministry of Health and Welfare MOHW107-CDC-C-114-000117Ministry of Science and Technology, Taiwan MOST104-2321-B-002-058Wanfang Hospital 108-wf-eva-12
6 · The paper itself

Abstract

While evidence is accumulating that platelets contribute to tissue destruction in tuberculosis (TB) disease, it is still not known whether antiplatelet agents are beneficial to TB patients. We performed this retrospective cohort study and identified incident TB cases in the Taiwan National Tuberculosis Registry from 2008 to 2014. These cases were further classified into antiplatelet users and non-users according to the use of antiplatelet agents prior to the TB diagnosis, and the cohorts were matched using propensity scores (PSs). The primary outcome was survival after a TB diagnosis. In total, 74,753 incident TB cases were recruited; 9497 (12.7%) were antiplatelet users, and 7764 (10.4%) were aspirin (ASA) users. A 1:1 PS-matched cohort with 8864 antiplatelet agent users and 8864 non-users was created. After PS matching, antiplatelet use remained associated with a longer survival (adjusted hazard ratio (HR): 0.91, 95% confidence interval (CI): 0.88-0.95,

Indexed as

antiplateletaspirinimmunomodulationsurvivalTaiwantuberculosis

Identifiers

PMID31252593
PMCPMC6678265
OpenAlexW2954337965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.