ArticleThe Journal of investigative dermatology2020
Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection.
Open access · bronzeAbstract readLetter
In one paragraph
Article in The Journal of investigative dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 51 citations in OpenAlex.
- Topical AuNPs-Cys-Sm29 gel modulates the course of lesion development in experimental cutaneous leishmaniasis.PLoS neglected tropical diseases · 2025Article
- Identification and experimental validation of mitochondrial and endoplasmic reticulum stress related gene in diabetic nephropathy.Scientific reports · 2025Article
- Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma.Nature communications · 2025Article
- Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole forPharmaceuticals (Basel, Switzerland) · 2024Article
- ThePathogens (Basel, Switzerland) · 2024Article
- Glyburide Suppresses Inflammation-Related Colorectal Tumorigenesis Through Inhibition of NLRP3 Inflammasome.International journal of molecular sciences · 2024Article
- Immunotherapeutic Strategies as Potential Treatment Options for Cutaneous Leishmaniasis.Vaccines · 2024Review
- The Role of Senescent CD8Pathogens (Basel, Switzerland) · 2024Article
- CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions.PLoS pathogens · 2024Article
- New Insights on NLRP3 Inflammasome: Mechanisms of Activation, Inhibition, and Epigenetic Regulation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024Review
- Article
- Targeting NLRP3 Inflammasome: Structure, Function, and Inhibitors.Current medicinal chemistry · 2024Article
- Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases.Cell death & disease · 2023Review
- The effects of Leishmania RNA virus 2 (LRV2) on the virulence factors of L. major and pro-inflammatory biomarkers: an in vitro study on human monocyte cell line (THP-1).BMC microbiology · 2023Article
- Prostaglandin E2 contributes toEmerging microbes & infections · 2023Article
- CCR5 promotes the migration of CD8bioRxiv : the preprint server for biology · 2023Article
- Article
- Immune Response to LinB13, a Lutzomyia Intermedia Salivary Protein Correlates With Disease Severity in Tegumentary Leishmaniasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- The level of interleukin-17, 23, and gamma interferon in cutaneous leishmaniasis patients before and after intra lesion treatment.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Protection and Pathology inPathogens (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Augusto M CarvalhoInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil; Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Fernanda O NovaisDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Camilla S PaixãoInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil.
Camila I de OliveiraInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil.
Paulo Roberto Lima MachadoInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil; Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil; Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (INCT-DT), Salvador, Bahia, Brazil.
Lucas P CarvalhoInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil; Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil; Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (INCT-DT), Salvador, Bahia, Brazil.
Phillip ScottDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Edgar M CarvalhoInstituto Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil; Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil; Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (INCT-DT), Salvador, Bahia, Brazil. Electronic address: imuno@ufba.br.
Universidade Federal da Bahia · BRFundação Oswaldo Cruz · BRUniversity of Pennsylvania · US
Funding
The role of Leishmania braziliensis strain polymorphism on disease outcome and ..P50AI030639 · NIAID · FEDERAL UNIVERSITY OF BAHIA · PI CARVALHO, EDGAR M · 1991 to 2023
$9.1MThe Role of Innate Cells in the Pathogenesis of Leishmania Braziliensis InfectionU01AI088650 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SCOTT, PHILLIP · 2011 to 2019
$4.3MInflammation in the Pathogenesis of Disseminated LeishmaniasisU01AI136032 · NIAID · FEDERAL UNIVERSITY OF BAHIA · PI CARVALHO, EDGAR M · 2017 to 2021
$1.6MNIAID NIH HHS P50 AI030639NIAID NIH HHS U01 AI088650NIAID NIH HHS U01 AI136032
Abstract
PubMed holds no abstract for this paper.
Indexed as
BiopsyBrazilCells, CulturedCytokinesEndemic DiseasesGlyburideHumansHypoglycemic AgentsInflammation MediatorsLeishmania braziliensisLeishmaniasis, CutaneousMacrophagesNLR Family, Pyrin Domain-Containing 3 ProteinSkinCytokinesGlyburideHypoglycemic AgentsInflammation MediatorsNLR Family, Pyrin Domain-Containing 3 Protein
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.