Evidence map›Paper›PMID 31251323›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Pyronaridine-artesunate Shows Promise as an Effective and Well-tolerated Treatment for Artemisinin-resistant Plasmodium falciparum Malaria.

John Okombo, David A Fidock

Abstract readComment
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  2. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

John OkomboDepartment of Microbiology & Immunology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.
David A FidockDepartment of Microbiology & Immunology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.

Funding

Defining P. falciparum resistance to artemisinin-based combination therapiesR01AI109023 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FIDOCK, DAVID A · 2014 to 2025
$4.4M
Elucidating the molecular basis of piperaquine resistance in Plasmodium falciparumR01AI124678 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI David A Fidock · 2016 to 2026
$4.3M
NIAID NIH HHS R01 AI109023NIAID NIH HHS R01 AI124678
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ArtemisininsMalaria, FalciparumArtesunateHumansNaphthyridinesVietnamArtemisininsArtesunateNaphthyridinespyronaridineartemisinin-based combination therapyclinical trialdrug resistanceK13Plasmodium falciparum malaria

Identifiers

PMID31251323
PMCPMC8494013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.