Evidence map›Paper›PMID 31251077›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Prolongation of bronchopulmonary C-fiber-mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT

Lei Zhao, Xiuping Gao, Jianguo Zhuang, Morgan Wallen, Shuguang Leng, Fadi Xu

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lei Zhao *Pathophysiological Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.
Xiuping Gao *Pathophysiological Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.
Jianguo ZhuangPathophysiological Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.
Morgan WallenDepartment of Arts and Sciences, University of Tennessee, Knoxville, Tennessee, USA.
Shuguang LengPathophysiological Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.
Fadi XuPathophysiological Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.
Lovelace Respiratory Research Institute · USUniversity of Tennessee at Knoxville · US

Funding

Lethal H5N1 Virus Infection and Respiratory DisordersR01HL119683 · NHLBI · LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE · PI XU, FADI · 2013 to 2016
$2.1M
Effect of Prenatal Nicotinic Exposure on Control of Hypoxic Ventilatory ResponseR01HL107462 · NHLBI · LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE · PI XU, FADI · 2011 to 2014
$1.7M
NHLBI NIH HHS R01 HL107462NHLBI NIH HHS R01 HL119683
6 · The paper itself

Abstract

Prenatal nicotinic exposure (PNE) reportedly sensitizes bronchopulmonary C-fibers (PCFs) and prolongs PCF-mediated apnea in rat pups, contributing to the pathogenesis of sudden infant death syndrome. Serotonin, or 5-hydroxytryptamine (5-HT), induces apnea

Indexed as

AnimalsAnimals, NewbornApneaBiguanidesBronchoalveolar Lavage FluidDisease Models, AnimalFemaleHumansInfant, NewbornLungMaleNerve Fibers, UnmyelinatedNicotinePregnancyPrenatal Exposure Delayed EffectsRatsBiguanidesNicotinephenyl biguanideReceptors, Serotonin, 5-HT3RNA, MessengerSerotoninSerotonin 5-HT3 Receptor Agonistscardiovascular activitysudden infant death syndromeTRPV1vagal sensory neurons

Identifiers

PMID31251077
PMCPMC6766661
OpenAlexW2954308238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.