Evidence map›Paper›PMID 31250576›Full record

Trial reportYonsei medical journal2019

Comparison of Apixaban and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis after Total Knee Arthroplasty in Older Adults.

Hui Jiang, Jia Meng, Ting Guo, Jian Ning Zhao, Yi Cun Wang, Jun Wang, Yang Qiu, Hao Ding

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Yonsei medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui Jiang *Department of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0002-0419-8128
Jia Meng *Department of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0002-8121-8882
Ting GuoDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China. guoting439h@163.com.ORCID https://orcid.org/0000-0002-6417-999X
Jian Ning ZhaoDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China. zhaojianning578h@163.com.ORCID https://orcid.org/0000-0002-0093-4423
Yi Cun WangDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0003-4067-1637
Jun WangDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0003-2557-4978
Yang QiuDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0003-2537-882X
Hao DingDepartment of Orthopedics, Jinling Hospital, Nanjing Clinical School of the Second Military Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0003-2688-3852

Funding

Chinese Medical Doctor Association 2015COS0810Nanjing General Hospital 2017003
6 · The paper itself

Abstract

purposeTo compare the effect of apixaban and low molecular weight heparin (LMWH) in the prevention and treatment of deep venous thrombosis (DVT) after total knee arthroplasty in older adult patients. MATERIALS AND

methodsA total of 220 patients (average age of 67.8±6.4 years) undergoing total knee arthroplasty were randomly selected as research subjects and were divided into apixaban and LMWH groups (110 in each group).

resultsThe incidence of DVT was lower in the apixaban group than in the LMWH group (5.5% vs. 20.0%,

conclusionApixaban, which elicits fewer adverse reactions and is safer than LMWH, exhibited better effects in the prevention and treatment of DVT after total knee arthroplasty in older adults.

Indexed as

AgedAnticoagulantsArthroplasty, Replacement, KneeFemaleHeparin, Low-Molecular-WeightHumansMalePyrazolesPyridonesTime FactorsVenous ThrombosisAnticoagulantsapixabanHeparin, Low-Molecular-WeightPyrazolesPyridonesApixabandeep venous thrombosislow molecular weight heparintotal knee arthroplasty

Identifiers

PMID31250576
PMCPMC6597473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.