Evidence map›Paper›PMID 31250481›Full record

ArticleMagnetic resonance in medicine2019

In vivo validation of T2- and susceptibility-based S

Xin Miao, Krishna S Nayak, John C Wood

Open access · greenAbstract readValidation Study
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  4. Review
  5. Capillary transit time heterogeneity inhibits cerebral oxygen metabolism in patients with reduced cerebrovascular reserve capacity from steno-occlusive disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  6. Article
  7. Article
  8. Metabolism of oxygen via TMagnetic resonance in medicine · 2022
    Article
  9. Review
  10. Article
  11. Comparison of MRI methods for measuring whole-brain oxygen extraction fraction under different geometric conditions at 7T.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xin MiaoDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California.ORCID 0000-0002-7812-5423
Krishna S NayakDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California.ORCID 0000-0001-5735-3550
John C WoodDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California.ORCID 0000-0003-0996-3439
University of Southern California · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Neuromodulatory Mechanisms and Regional Autonomic Dysregulation in the Development of Pain in Sickle Cell Disease PatientsU01HL117718 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI COATES, THOMAS DUANE, KHOO, MICHAEL C K · 2013 to 2017
$9.6M
Cerebrovascular reserve and white matter disease in patients with anemiaR01HL136484 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI WOOD, JOHN C · 2018 to 2021
$2.5M
Optimizing Tissue Iron Quantification at 3 TeslaR01DK097115 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI WOOD, JOHN C · 2013 to 2016
$1.6M
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NHLBI NIH HHS R01 HL136484NHLBI NIH HHS U01 HL117718NIDDK NIH HHS R01 DK097115
6 · The paper itself

Abstract

purposeTo investigate the mutual agreement of T2-based and susceptibility-based methods as well as their agreement with jugular catheterization, for quantifying venous oxygen saturation (S

methodsS

resultsAbsolute S

conclusionA systematic bias was observed between T2-based and susceptibility-based methods that depended on the oxygenation state. In vivo validation with jugular catheterization indicated potential underestimation of TRUST under room air and hypoxia conditions. Our findings suggested that caution should be employed in comparison of absolute S

Indexed as

Magnetic Resonance ImagingOximetryAdultAirBrainCatheterizationCerebrovascular CirculationFemaleHealthy VolunteersHematocritHumansHypercapniaHypoxiaImage Processing, Computer-AssistedJugular VeinsMaleOxygenbrain oxygenationsusceptometry-based oximetryT2-relaxation-under-spin-taggingvenous oxygen saturation

Identifiers

PMID31250481
PMCPMC6717011
OpenAlexW2956075265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.