Evidence map›Paper›PMID 31250405›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2019

Biofilm inhibition, modulation of virulence and motility properties by FeOOH nanoparticle in Pseudomonas aeruginosa.

Dung Thuy Nguyen Pham, Fazlurrahman Khan, Thi Tuong Vy Phan, Seul-Ki Park, Panchanathan Manivasagan, Junghwan Oh, Young-Mog Kim

Open access · greenAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

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  12. Novel Strategies to Combat Bacterial Biofilms.Molecular biotechnology · 2021
    Review
  13. An Eco-Friendly Approach to the Control of Pathogenic Microbes andInternational journal of molecular sciences · 2021
    Article
  14. Review
  15. Silver Nanoparticles for the Therapy of Tuberculosis.International journal of nanomedicine · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dung Thuy Nguyen PhamDepartment of Food Science and Technology, Pukyong National University, Busan, 48513, South Korea.
Fazlurrahman KhanMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, South Korea.
Thi Tuong Vy PhanDepartment of Biomedical Engineering, Pukyong National University, Busan, 48513, South Korea.
Seul-Ki ParkDepartment of Food Science and Technology, Pukyong National University, Busan, 48513, South Korea.
Panchanathan ManivasaganMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, South Korea.
Junghwan OhMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, South Korea.
Young-Mog KimDepartment of Food Science and Technology, Pukyong National University, Busan, 48513, South Korea. ymkim@pknu.ac.kr.
Pukyong National University · KR

Funding

Ministry of Education 20150220
6 · The paper itself

Abstract

Biofilm formation is one of the resistance mechanisms of Pseudomonas aeruginosa against antimicrobial compounds. Biofilm formation also characterizes for the infection and pathogenesis of P. aeruginosa, along with production of various virulence factors. With recent development of nanotechnology, the present study aims to employ the synthetic iron nanoparticle (FeOOH-NP) as an active agent to inhibit the formation of P. aeruginosa biofilm. The FeOOH-NP was synthesized and characterized with rod shape and average size of 40 nm. Inhibition of biofilm formation by the FeOOH-NP is in a concentration-dependent manner, with inhibition of biofilm formation increased as the FeOOH-NP concentration increased. Microscopic observations also confirmed the disruption of the biofilm architecture in the presence of the FeOOH-NP. In addition, the presence of the FeOOH-NP was also found to modulate bacterial motility as well as some other important virulence factors produced simultaneously with biofilm formation. These findings provide insights to anti-biofilm effect of a new iron NP, contributing to the search for an effective agent to combat P. aeruginosa infections resulted from biofilm formation.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBiofilmsIronNanoparticlesPseudomonas aeruginosaVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsIronVirulence FactorsBiofilmIron nanoparticlesMotilityPseudomonas aeruginosaVirulence factors

Identifiers

PMID31250405
PMCPMC6863290
OpenAlexW2954146522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.