Evidence map›Paper›PMID 31250194›Full record

ArticleClinical oral investigations2020

Incidence of complications in secondary alveolar bone grafting of bilateral clefts with premaxillary osteotomy: a retrospective cohort study.

Gerhard K P Bittermann, Robert J J van Es, Adrianus P de Ruiter, Michael H Frank, Arnold J N Bittermann, Aebele B Mink van der Molen, Ron Koole, Antoine J W P Rosenberg

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Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gerhard K P BittermannDepartment of Oral and Maxillofacial Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, PO Box 85500, 3508 AB, Utrecht, The Netherlands. g.k.p.bittermann@umcutrecht.nl.
Robert J J van EsDepartment of Oral and Maxillofacial Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, PO Box 85500, 3508 AB, Utrecht, The Netherlands.
Adrianus P de RuiterDepartment of Oral and Maxillofacial Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, PO Box 85500, 3508 AB, Utrecht, The Netherlands.
Michael H FrankDepartment of Oral and Maxillofacial Surgery, Haaglanden Medical Centre, PO Box 432, 2501 CK, The Hague, The Netherlands.
Arnold J N BittermannDepartment of Pediatric Otorhinolaryngology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3508 AB, Utrecht, The Netherlands.
Aebele B Mink van der MolenDepartment of Plastic Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Lundlaan 6, PO Box 85090, 3508 AB, Utrecht, The Netherlands.
Ron KooleDepartment of Oral and Maxillofacial Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, PO Box 85500, 3508 AB, Utrecht, The Netherlands.
Antoine J W P RosenbergDepartment of Oral and Maxillofacial Surgery, Wilhelmina Children's Hospital Cleft Team, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, PO Box 85500, 3508 AB, Utrecht, The Netherlands.
Utrecht University · NLWilhelmina Children's Hospital · NLMedisch Centrum Haaglanden · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate factors affecting incidence of complications after secondary alveolar bone grafting with premaxillary osteotomy (SABG + PO) in children with complete bilateral cleft of lip and palate (BCLP). MATERIALS AND

methodsData were collected from children with BCLP treated with SABG + PO from 2004 to 2014 at our institute. Preoperative parameters included age, donor site, race, gingival health, bone quality around cleft-related teeth, premaxilla position, graft timing, presence of canines in the cleft, and presence of deciduous teeth around the cleft area. Logistic regression and the chi-squared test were used to assess correlations and the incidence of complications.

resultsIn the 64 patients, a significant correlation was found between complication rate and timing of bone grafting with respect to early versus late SABG + PO (p = 0.041), age > 12 years (p = 0.011; odds ratio (OR) 5.9; 95% confidence interval (CI) 1.49-23.93), malposition of the premaxilla (p = 0.042; OR 3.3; 95% CI 1.04-10.13), and preoperative bone quality around cleft-related teeth (p = 0.005; OR 5.3; 95% CI 1.6-17.2).

conclusionsThe timing of SABG + PO is essential, as early SABG + PO is associated with fewer complications. A malpositioned premaxilla and poor bone quality around cleft-related teeth are associated with more complications. Therefore, preoperative orthodontic repositioning of the malpositioned premaxilla before SABG + PO should be considered. CLINICAL RELEVANCE: Analysis of treatment protocols and complications for BCLP patients underscores that proper timing of SABG + PO and correct premaxilla repositioning help reduce complications.

Indexed as

Alveolar Bone GraftingBone TransplantationChildCleft LipCleft PalateHumansIncidenceMaxillaOsteotomyRetrospective StudiesAlveolar cleftBilateral cleft lip and palatePediatric dentistryPremaxillary osteotomyReoperationSecondary alveolar bone grafting

Identifiers

PMID31250194
OpenAlexW2953885514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.