Evidence map›Paper›PMID 31250135›Full record

ReviewCurrent oncology reports2019

Acute Myeloid Leukemia: Update on Upfront Therapy in Elderly Patients.

Gina Keiffer, Neil Palmisiano

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gina KeifferThomas Jefferson University Hospital, 834 Chestnut St, Suite 315, Philadelphia, PA, 19107, USA. gina.keiffer@jefferson.edu.
Neil PalmisianoThomas Jefferson University Hospital, 834 Chestnut St, Suite 315, Philadelphia, PA, 19107, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAcute myeloid leukemia (AML) disproportionately impacts elderly patients. Treating elderly patients with AML has been a challenge due to the increased prevalence of medical comorbidities and decreased performance status in this population, as well as the different biology of AML in elderly patients. RECENT

findingsThe care of elderly patients with AML has advanced significantly over the past few years. Our greater understanding of the biology of AML in elderly patients has led to the development of novel, lower-intensity treatment options. We present here a review of the most recent literature regarding therapeutic options available to older patients, as well as tools to help identify the right treatment for the right patient. As targeted and lower-intensity treatment options become available, developing an approach to "right size" therapy for individual elderly patients is paramount.

Indexed as

AgedAntineoplastic AgentsClinical Decision-MakingGeriatricsHumansInduction ChemotherapyLeukemia, Myeloid, AcuteMedical OncologyPrecision MedicineRisk AssessmentAntineoplastic AgentsAcute myeloid leukemiaElderly AMLSecondary AMLTherapy-related AMLUpfront therapy

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.