Evidence map›Paper›PMID 31250095›Full record

ArticlePflugers Archiv : European journal of physiology2019

Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca

Christine Deisl, Michael Fine, Orson W Moe, Donald W Hilgemann

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The role of hormones and neurons in cardiomyocyte maturation.Seminars in cell & developmental biology · 2021
    Review
  8. Article
  9. A new stone for a new path, from "physiology to the bedside".Pflugers Archiv : European journal of physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christine DeislDepartments of Physiology and Internal Medicine, Charles and Jane Pak Center of Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA. Christine.deisl@utsouthwestern.edu.
Michael FineDepartments of Physiology and Internal Medicine, Charles and Jane Pak Center of Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA.
Orson W MoeDepartments of Physiology and Internal Medicine, Charles and Jane Pak Center of Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA.
Donald W HilgemannDepartments of Physiology and Internal Medicine, Charles and Jane Pak Center of Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA. Donald.hilgemann@utsouthwestern.edu.ORCID 0000-0002-5288-5133
Southwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Klotho and Phosphate in Chronic Kidney Disease: Pathogenesis and TherapeuticsR01DK091392 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI HU, MING-CHANG, MOE, ORSON W · 2011 to 2021
$3.2M
Palmitoylation-dependent massive endocytosis (pMEND)R01HL119843 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILGEMANN, DONALD W · 2014 to 2021
$3.1M
American Heart Association-American Stroke Association FellowshipNHLBI NIH HHS R01 HL119843NIDDK NIH HHS R01 DK091392NIH HHS HL119843
6 · The paper itself

Abstract

Human embryonic stem cell-derived cardiomyocytes develop pronounced hypertrophy in response to angiotensin-2, endothelin-1, and a selected mix of three fatty acids. All three of these responses are accompanied by increases in both basal cytoplasmic Ca

Indexed as

Calcium SignalingFeedback, PhysiologicalAngiotensin IICardiomegalyCell DifferentiationCells, CulturedDiglyceridesEndothelin-1Enzyme InhibitorsFemaleHuman Embryonic Stem CellsHumansMyocytes, CardiacOuabainSodiumSodium-Potassium-Exchanging ATPaseAngiotensin IIDiglyceridesEndothelin-1Enzyme InhibitorsOuabainSodiumSodium-Potassium-Exchanging ATPaseVasoconstrictor AgentsAngiotensin-2Cardiac glycosidesCardiac hypertrophyDiacylglycerol lipaseDO34Endothelin-1OuabainPatch clampSodium potassium pump

Identifiers

PMID31250095
PMCPMC6614165
OpenAlexW2954279955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.