SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2020
Similar results with kinematic and mechanical alignment applied in total knee arthroplasty.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06486714 (Mechanical Alignment Versus Kinematic Alignment Total Knee Arthroplasty), which is not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mechanical Alignment Versus Kinematic Alignment Total Knee Arthroplasty: A Randomized Control Trial
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Kinematic Alignment Does Not Result in Clinically Important Improvements After TKA Compared With Mechanical Alignment: A Meta-analysis of Randomized Trials.Clinical orthopaedics and related research · 2025Pooled it
- Postoperative clinical outcomes for kinematically, restricted kinematically, or mechanically aligned total knee arthroplasty: a systematic review and network meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2023Pooled it
- Kinematic alignment versus mechanical alignment in primary total knee arthroplasty: an updated meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2022Pooled it
- Comparison of Outcomes After Total Knee Arthroplasty Involving Postoperative Neutral or Residual Mild Varus Alignment: A Systematic Review and Meta-analysis.Orthopaedic surgery · 2022Pooled it
- Unrestricted kinematic alignment offers limited functional benefit over mechanical alignment in medial pivot total knee arthroplasty: A randomized controlled trial using conventional instrumentation.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Trial
- Randomized Controlled Trial of a Novel Cementless vs. Cemented Total Knee Arthroplasty: Early Clinical and Radiographic Outcomes.Orthopaedic surgery · 2024Trial
- Robotic-Assisted Kinematically Aligned Total Knee Arthroplasty Demonstrated Early Rehabilitation and Select Mental Health-Related Quality of Life Improvements Compared to Conventional MA-TKA.Journal of clinical medicine · 2026Article
- Robot-Assisted TKA for Varus Knees: Post Hoc Exploratory Analysis of Alignment Strategy and Deformity Severity.Journal of clinical medicine · 2026Article
- Analysis of CPAK change in robotic functional alignment TKA: a new simplified classification.Archives of orthopaedic and trauma surgery · 2026Article
- Kinematic alignment in total knee arthroplasty restores the native anatomy, with a joint line parallel to the ground on a standing view.Journal of orthopaedics · 2025Article
- Lateral Instability 13 Years After Kinematically Aligned Total Knee Arthroplasty.Arthroplasty today · 2025Article
- Improvement in gait pattern after total knee arthroplasty for knee osteoarthritis.Journal of experimental orthopaedics · 2025Article
- CORR Insights®: No Difference in 10-year Clinical or Radiographic Outcomes Between Kinematic and Mechanical Alignment in TKA: A Randomized Trial.Clinical orthopaedics and related research · 2025Article
- Novel technique for achieving the under-correction of native tibial varus in calipered restricted kinematically aligned total knee arthroplasty - A validation study.Journal of clinical orthopaedics and trauma · 2024Article
- Kinematic versus mechanical alignment: A systematic review of systematic reviews and meta-analyses of randomised controlled trials.Journal of experimental orthopaedics · 2024Review
- The Viability and Success of Noncemented Kinematic Total Knee Arthroplasty.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024Article
- Unveiling distinct kinematic profiles among total knee arthroplasty candidates through clustering technique.Journal of orthopaedic surgery and research · 2024Article
- No difference in postoperative patient satisfaction rates between mechanical and kinematic alignment total knee arthroplasty: A systematic review.Journal of experimental orthopaedics · 2024Review
- Methods of alignment in total knee arthroplasty, systematic review.Orthopedic reviews · 2024Article
- Systematic review and meta-analysis of long term outcomes and innovations in Total Knee Arthroplasty: KINEMATIC, PERSONALIZED KNEE vs. CONVENTIONAL.Orthopedic reviews · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis meta-analysis compared the results of kinematic alignment (KA) and mechanical alignment (MA) applied in total knee arthroplasty (TKA).
methodsRandomized controlled trials and cohort studies comparing functional, radiological, and perioperative results and complications in TKA with KA and MA were collected from databases and included in the analysis.
resultsNine trials were included. KA showed a better performance in terms of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (mean difference [MD] = - 9.06, 95% confidence interval [CI] - 14.69, - 3.42) and Oxford knee score (OKS) (MD = 4.72, 95% CI 0.24, 9.21); however, the Knee Society score (KSS), knee injury and osteoarthritis outcome score (KOOS), EuroQoL 5-dimension questionnaire (ED-5D), range of motion, and complications were similar for KA and MA (n.s.). KA resulted in slightly more varus alignment in the tibia [mechanical medial proximal tibial angle (mMPTA) MD = - 2.45, 95% CI - 2.89, - 2.01) and more valgus alignment in the femur (mLDFA MD = - 2.06, 95% CI - 2.48, - 1.65) than MA (P < 0.05), but showed similar results in terms of the joint line orientation angle (JLOA) (MD = 0.54, 95% CI - 2.59, 3.66), hip-knee-ankle angle (HKA), anatomical knee angle (AKA), femoral flexion-extension angle (FFA), and tibial slope (TS). The preoperative results, including the incision length, hospital stay, and changes in hemoglobin, were also similar.
conclusionKA achieved functional, radiological, and perioperative results similar to those of MA and did not increase the complication rate. KA is an acceptable and satisfactory method for application in TKA. LEVEL OF EVIDENCE: III.
Indexed as
Identifiers
31250055What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.