ArticleDer Radiologe2019
[Atraumatic and aseptic osteonecrosis of large joints].
Article in Der Radiologe, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- [Differential diagnoses of osteonecrosis of large joints].Der Orthopade · 2019Article
- [Differential diagnoses of osteonecrosis of large joints].Der Radiologe · 2019Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
Subchondral osteonecrosis of large weight-bearing joints (hip and knee joints) represents a severe and joint-threatening disease. Apart from idiopathic forms, glucocorticoid medication and alcohol abuse have been identified as major causative factors for atraumatic osteonecrosis. In addition to direct cytotoxic factors, a critically reduced perfusion of the subchondral osseous space will eventually lead to bone marrow ischemia and osseous necrosis. Magnetic resonance imaging (MRI) is capable of visualizing a reactive border-like zone in this early, already irreversible and often asymptomatic stage I according to the Association of Research Circulation Osseous (ARCO) staging system. Later in the course, osteonecrosis progresses to form serpiginous sclerotic lines, enclosing the necrotic bone area (stage II ARCO). Repair mechanisms of osteonecrosis are mostly unsuccessful and depending on the size of the osteonecrosis result in biomechanical failure and ultimately subchondral insufficiency fractures (crescent sign), thus marking the transition to stage III ARCO (joint surface collapse).
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Registered trials
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