ArticleJNCI cancer spectrum2018
Radiation Risks of Uterine Cancer in Atomic Bomb Survivors: 1958-2009.
Article in JNCI cancer spectrum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958-2009.Carcinogenesis · 2025Article
- Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring.Carcinogenesis · 2025Review
- Recent evolution of risk analyses in atomic bomb survivor studies: new methods and applications.Carcinogenesis · 2025Review
- The importance of data from the atomic bomb survivors for international radiological protection.Carcinogenesis · 2025Article
- Trans-Scale Insights into Variability in Radiation Cancer Risk Across Tissues, Individuals, and Species.Biology · 2025Review
- Establishment and activity of the planning and acting network for low dose radiation research in Japan (PLANET): 2016-2023.Journal of radiation research · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Cervical and Endometrial Cancer Incidence in the Female Population from the Bryansk Region Living in Conditions of Chemical, Radioactive and Combined Environmental Contamination (2000-2020).Life (Basel, Switzerland) · 2022Article
- The importance of addressing early life environmental exposures in cancer epidemiology.Current epidemiology reports · 2022Article
- Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022Article
- Comparison of All Solid Cancer Mortality and Incidence Dose-Response in the Life Span Study of Atomic Bomb Survivors, 1958-2009.Radiation research · 2022Article
- Review of the risk of cancer following low and moderate doses of sparsely ionising radiation received in early life in groups with individually estimated doses.Environment international · 2022Review
- Age effects on radiation response: summary of a recent symposium and future perspectives.International journal of radiation biology · 2022Article
- Estimation of radiation doses and lifetime attributable risk of radiation-induced cancer in the uterus and prostate from abdomen pelvis CT examinations.Frontiers in public health · 2022Article
- Ovarian Malignancies Frequency in the Female Population from the Bryansk Region Living in Conditions of Radioactive, Chemical and Combine Contamination (2000-2020).Life (Basel, Switzerland) · 2021Article
- Risk of Prostate Cancer Incidence among Atomic Bomb Survivors: 1958-2009.Radiation research · 2021Article
- Radiation Risk of Ovarian Cancer in Atomic Bomb Survivors: 1958-2009.Radiation research · 2021Article
- ProZES: the methodology and software tool for assessment of assigned share of radiation in probability of cancer occurrence.Radiation and environmental biophysics · 2020Article
- Individual response of humans to ionising radiation: governing factors and importance for radiological protection.Radiation and environmental biophysics · 2020Review
- Identifying Scoliosis in Population-Based Cohorts: Automation of a Validated Method Based on Total Body Dual Energy X-ray Absorptiometry Scans.Calcified tissue international · 2020Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIonizing radiation is known to be capable of causing cancer of many organs, but its relationship with uterine cancer has not been well characterized.
methodsWe studied incidence of uterine cancer during 1958-2009 among 62 534 female atomic bomb survivors. Using Poisson regression analysis, we fitted excess relative risk (ERR) models to uterine cancer rates adjusted for several lifestyle and reproductive factors. Person-years at risk were also adjusted for the probability of prior hysterectomy, because it could affect the subsequent risk of uterine cancer. We assessed the modifying effect of age and other factors on the radiation risk. For analysis of the modifying effect of age at radiation exposure around menarche, we compared the radiation risk for several exposure-age categories as well as using parametric models.
resultsThere were 224 uterine corpus cancers and 982 cervical cancers. We found a significant association between radiation dose and risk of corpus cancer (ERR per Gray [ERR/Gy] = 0.73, 95% confidence interval [CI] = 0.03 to 1.87) but not for cervical cancer (ERR/Gy = 0.00, 95% CI = -0.22 to 0.31). For corpus cancer, we found statistically significant heterogeneity in ERR/Gy by age (
conclusionsThe current data suggest that uterine corpus is especially sensitive to the carcinogenic effect of radiation exposure occurring during the mid-pubertal period preceding menarche. There is little evidence for a radiation effect on cervical cancer risk.
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