Evidence map›Paper›PMID 31249960›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2018

Activity Pattern Analysis Indicates Increased but Balanced Systemic Coagulation Activity in Response to Surgical Trauma.

Max Julian Friedrich, Jan Schmolders, Yorck Rommelspacher, Andreas Strauss, Heiko Rühl, Günter Mayer, Johannes Oldenburg, Dieter Christian Wirtz, Jens Müller, Bernd Pötzsch

Open access · goldAbstract read
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Renal transplant and hemostasis: early postoperative changes in recipients and donors.Research and practice in thrombosis and haemostasis · 2023
    Article
  2. Plasmatic coagulation profile after major traumatic injury: a prospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Observational
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Simulated Hypergravity Activates Hemostasis in Healthy Volunteers.Journal of the American Heart Association · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Max Julian FriedrichDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Jan SchmoldersDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Yorck RommelspacherDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Andreas StraussDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Heiko RühlInstitute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Günter MayerLife and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany.
Johannes OldenburgInstitute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Dieter Christian WirtzDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Jens MüllerInstitute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Bernd PötzschInstitute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the nonbleeding patient, constant low-level activation of coagulation enables a quick procoagulant response upon an injury. Conversely, local activation of coagulation might influence the systemic activity level of coagulation. To characterize this interaction in more detail, activity pattern analysis was performed in patients undergoing elective surgeries. Blood samples were taken before, during, and 24 hours after surgery from 35 patients undergoing elective minor (

Indexed as

biomarkerscoagulationDNA aptamersenzyme activitysurgical hemostasis

Identifiers

PMID31249960
PMCPMC6524900
OpenAlexW2894978293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.