Evidence map›Paper›PMID 31249954›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2018

Orphan Three-Finger Toxins Bind at Tissue Factor-Factor VIIa Interface to Inhibit Factor X Activation: Identification of Functional Site by Docking.

Manisha Choudhury, Ryan J R McCleary, R Manjunatha Kini, Devadasan Velmurugan

Open access · goldAbstract read
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Manisha ChoudhuryCAS in Crystallography and Biophysics, University of Madras, Chennai, Tamil Nadu, India.
Ryan J R McClearyDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
R Manjunatha KiniDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Devadasan VelmuruganCAS in Crystallography and Biophysics, University of Madras, Chennai, Tamil Nadu, India.
University of Madras · INNational University of Singapore · SGStetson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-finger toxins (3FTxs) contribute to toxicity of venomous snakes belonging to the family Elapidae. Currently, functions of a considerable proportion of 3FTxs are still unknown. Here, we describe the function of orphan group I 3FTxs consisting of four members. We also identified a new member of this group by sequencing a transcript isolated from

Indexed as

anticoagulantextrinsic tenase complexfactor VIIa–tissue factor complex inhibitororphan group I toxins

Identifiers

PMID31249954
PMCPMC6524886
OpenAlexW2893697577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.