Evidence map›Paper›PMID 31249917›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2017

Cigarette Smoke Extract Inhibits Platelet Aggregation by Suppressing Cyclooxygenase Activity.

Hitoshi Kashiwagi, Koh-Ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Tsunehito Higashi, Takahiro Horinouchi, Soichi Miwa, Shuh Narumiya, Fumitaka Ushikubi

Open access · goldAbstract read
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparable Impairment of Vascular Endothelial Function by a Wide Range of Electronic Nicotine Delivery Devices.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
  4. Article
  5. E-Cigarettes and Cardiopulmonary Health.Function (Oxford, England) · 2021
    Review
  6. Happy New Year!TH open : companion journal to thrombosis and haemostasis · 2019
    Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hitoshi KashiwagiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Koh-Ichi YuhkiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Yoshitaka ImamichiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Fumiaki KojimaCore Research for Evolutional Science and Technology, Japan Science and Technology Agency, Tokyo, Japan.
Shima KumeiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Tsunehito HigashiDepartment of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Takahiro HorinouchiDepartment of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Soichi MiwaDepartment of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Shuh NarumiyaCore Research for Evolutional Science and Technology, Japan Science and Technology Agency, Tokyo, Japan.
Fumitaka UshikubiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Japan Science and Technology Agency · JPAsahikawa Medical University · JPHokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The results of studies that were performed to determine whether cigarette smoking affects platelet function have been controversial, and the effects of nicotine- and tar-free cigarette smoke extract (CSE) on platelet function remain to be determined. The aim of this study was to determine the effect of CSE on platelet aggregation and to clarify the mechanism by which CSE affects platelet function. CSE inhibited murine platelet aggregation induced by 9,11-dideoxy-9α,11α-methanoepoxy-prosta-5Z,13E-dien-1-oic acid (U-46619), a thromboxane (TX) A

Indexed as

cigarette smoke extractcyclooxygenaseplateletsthromboxane A 2

Identifiers

PMID31249917
PMCPMC6524849
OpenAlexW2767099543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.