Evidence map›Paper›PMID 31249834›Full record

ArticleFrontiers in nutrition2019

Whey Protein Supplementation Post Resistance Exercise in Elderly Men Induces Changes in Muscle miRNA's Compared to Resistance Exercise Alone.

Randall F D'Souza, Nina Zeng, James F Markworth, Vandre C Figueiredo, Christopher P Hedges, Aaron C Petersen, Paul A Della Gatta, David Cameron-Smith, Cameron J Mitchell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Non-coding RNAs in exercise immunology: A systematic review.Journal of sport and health science · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
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  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Randall F D'SouzaLiggins Institute, The University of Auckland, Auckland, New Zealand.
Nina ZengLiggins Institute, The University of Auckland, Auckland, New Zealand.
James F MarkworthLiggins Institute, The University of Auckland, Auckland, New Zealand.
Vandre C FigueiredoLiggins Institute, The University of Auckland, Auckland, New Zealand.
Christopher P HedgesApplied Surgery and Metabolism Laboratory, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Aaron C PetersenInstitute for Health and Sport (iHeS), Victoria University, Melbourne, VIC, Australia.
Paul A Della GattaInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia.
David Cameron-SmithLiggins Institute, The University of Auckland, Auckland, New Zealand.
Cameron J MitchellLiggins Institute, The University of Auckland, Auckland, New Zealand.
University of Auckland · NZDeakin University · AUUniversity of Kentucky · USUniversity of Michigan · USVictoria University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive muscle loss with aging results in decreased physical function, frailty, and impaired metabolic health. Deficits in anabolic signaling contribute to an impaired ability for aged skeletal muscle to adapt in response to exercise and protein feeding. One potential contributing mechanism could be exerted by dysregulation of microRNAs (miRNAs). Therefore, the aim of this study was to determine if graded protein doses consumed after resistance exercise altered muscle miRNA expression in elderly men. Twenty-three senior men (67.9 ± 0.9 years) performed a bout of resistance exercise and were randomized to consume either a placebo, 20 or 40 g of whey protein (

Indexed as

microRNAmTOR pathwayolder adultsP70S6 Kprotein doseresistance trainingskeletal muscle

Identifiers

PMID31249834
PMCPMC6582369
OpenAlexW2950351198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.