ReviewFrontiers in pediatrics2019
Congenital Lung Malformations: Unresolved Issues and Unanswered Questions.
Review in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- The value of fetal magnetic resonance imaging in diagnosis of congenital anomalies of the fetal body: a systematic review and meta-analysis.BMC medical imaging · 2024Pooled it
- Is thoracoscopy superior to thoracotomy in the treatment of congenital lung malformations? An updated meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Management and outcomes of congenital pulmonary airway malformations and bronchopulmonary sequestrations diagnosed in the fetal period.Pediatric surgery international · 2026Article
- Navigating the spectrum: a comprehensive approach to fetal lung abnormalities in ultrasound and magnetic resonance imaging.Pediatric radiology · 2026Review
- Genetic Disorders Detectable by Fetal MRI: A Review.Diagnostics (Basel, Switzerland) · 2026Review
- Lobectomy vs. sublobar resection for congenital pulmonary airway malformations: a 10-year NSQIP-pediatric review.Pediatric surgery international · 2026Article
- Article
- Surgical Management of Congenital Lung Malformations in Children-A Single-Center Analysis of 25 Years of Experience.The clinical respiratory journal · 2026Article
- Diffuse cystic lung diseases-a primer for radiologists.BJR open · 2026Review
- Robotic-assisted thoracic surgery in children with congenital lung disease: advancements, challenges, and future directions.Frontiers in pediatrics · 2026Review
- Thoracoscopic surgery for symptomatic congenital lung malformations in neonates: a retrospective study of 36 cases.BMC pulmonary medicine · 2025Article
- Advances in Fetal Surgery: A Narrative Review of Therapeutic Interventions and Future Directions.Medicina (Kaunas, Lithuania) · 2025Review
- Article
- Natural course of CPAM and pulmonary sequestration: to operate or not to operate, this is the question.Pediatric pulmonology · 2025Review
- Clinical outcomes after surgical resection in asymptomatic and symptomatic children with congenital lung malformations.Journal of cardiothoracic surgery · 2025Article
- The potential of Real-Time rendered-volume 3D Imaging in immersive virtual-reality (VR) for surgical planning in infants with congenital thoracic malformation (CTM).Computational and structural biotechnology journal · 2025Article
- Factors affecting inflammatory changes in congenital lung malformations.Pediatric surgery international · 2024Article
- The ten-year evaluation of clinical characteristics in congenital lung anomaly in pediatrics; a retrospective study in North of Iran.BMC pediatrics · 2024Article
- Beyond Bronchopulmonary Dysplasia: A Comprehensive Review of Chronic Lung Diseases in Neonates.Cureus · 2024Review
- Congenital Lung Malformations: A Pictorial Review of Imaging Findings and a Practical Guide for Diagnosis.Children (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in prenatal and postnatal diagnosis, perioperative management, and postoperative care have dramatically increased the number of scientific reports on congenital thoracic malformations (CTM). Nearly all CTM are detected prior to birth, generally by antenatal ultrasound. After delivery, most infants do well and remain asymptomatic for a long time. However, complications may occur beyond infancy, including in adolescence and adulthood. Prenatal diagnosis is sometimes missed and detection may occur later, either by chance or because of unexplained recurrent or persistent respiratory symptoms or signs, with difficult implications for family counseling and substantial delay in surgical planning. Although landmark studies have been published, postnatal management of asymptomatic children is still controversial and needs a resolution. Our aim is to provide a focused overview on a number of unresolved issues arising from the lack of an evidence-based consensus on the management of patients with CTM. We summarized findings from current literature, with a particular emphasis on the vigorous controversies on the type and timing of diagnostic procedures, treatments and the still obscure relationship between CTM and malignancies, a matter of great concern for both families and physicians. We also present an algorithm for the assessment and follow-up of CTM detected either in the antenatal or postnatal period. A standardized approach across Europe, based on a multidisciplinary team, is urgently needed for achieving an evidence-based management protocol for CTM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.