Difficult diagnosis and rare morphology of lymphangioleiomyomatosis with giant cysts.

Stefan Welter, Philipp Thrull, Michael Westhoff, Peter Bach, Helmut Popper, Hans-Jörg Maschek

Open access · goldAbstract readCase Reports

In one paragraph

Article in Respiratory medicine case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 92% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Stefan WelterLung Clinic Hemer, Center for Pneumology and Thoracic Surgery, Theo-Funccius-Str. 1, 58675 Hemer, Germany.

Philipp ThrullLung Clinic Hemer, Center for Pneumology and Thoracic Surgery, Theo-Funccius-Str. 1, 58675 Hemer, Germany.

Michael WesthoffLung Clinic Hemer, Center for Pneumology and Thoracic Surgery, Theo-Funccius-Str. 1, 58675 Hemer, Germany.

Peter BachLung Clinic Hemer, Center for Pneumology and Thoracic Surgery, Theo-Funccius-Str. 1, 58675 Hemer, Germany.

Helmut PopperInstitute of Pathology, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.

Hans-Jörg MaschekSynlab, Pathology Laboratory, Tiergartenstraße 73, 30559 Hannover, Germany.

Lungenklinik Hemer · DEMedical University of Graz · ATSynlab (Germany) · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a 32-year-old woman with a second manifestation of a tension pneumothorax two weeks after drainage therapy. The chest CT-scan revealed multiple large bilateral pulmonary cysts. She underwent minimally invasive wedge resection and pleurectomy for treatment. The extensive histologic evaluation revealed the diagnosis of a lymphangioleiomyomatosis (LAM) with an uncommon pattern of lung cysts. Initial staining for HMB-45 was negative. Repeated evaluation of other sections and reference pathology examination detected minimal expression of HMB-45. This case illustrates that immunohistochemistry for HMB-45 may be negative, although LAM is present and repeated immunohistochemistry may be necessary to establish the correct diagnosis.

Indexed as

Lung cystsLymphangioleiomyomatosisPneumothorax

Identifiers

PMID31249775

DOI10.1016/j.rmcr.2019.100873

PMCPMC6586772

OpenAlexW2948957946

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.