Evidence map›Paper›PMID 31249677›Full record

ArticleF1000Research2019

Case Report: Ocular toxoplasmosis in a WHIM syndrome immunodeficiency patient.

David H McDermott, Lauren E Heusinkveld, Wadih M Zein, H Nida Sen, Martha M Marquesen, Mark Parta, Sergio D Rosenzweig, Gary A Fahle, Michael D Keller, Henry E Wiley and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Frontiers in cellular and infection microbiology · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

David H McDermottLaboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Lauren E HeusinkveldLaboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Wadih M ZeinNational Eye Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA.
H Nida SenNational Eye Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Martha M MarquesenLaboratory of Clinical Immunology and Microbiology, National Institute Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Mark PartaClinical Research Directorate/Clinical Monitoring Research Program, Bethesda, MD, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Bethesda, Maryland, 20892, USA.
Sergio D RosenzweigDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Gary A FahleDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Michael D KellerDivision of Allergy & Immunology, Children's National Medical Center, Washington, DC, 20010, USA.
Henry E WileyNational Eye Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Philip M MurphyLaboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID 0000-0002-1080-8201
National Institutes of Health · USNational Institutes of Health Clinical Center · USChildren's National · USFrederick National Laboratory for Cancer Research · US

Funding

Molecular Analysis Of Leukocyte Activation By ChemoattractantsZIAAI000615 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MURPHY, PHILIP · 2009 to 2025
$44.8M
Studies of Inherited Causes of Fungal SusceptabilityZIAAI001122 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROSENZWEIG, SERGIO · 2010 to 2025
$26.0M
Mutation Analysis Of Selected Lymphoid Immune DisordersZIACL010304 · CLC · CLINICAL CENTER · PI ROSENZWEIG, SERGIO · 2009 to 2025
$0k
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

A patient with WHIM syndrome immunodeficiency presented with sudden painless right eye blindness associated with advanced retinal and optic nerve damage.

Indexed as

Primary Immunodeficiency DiseasesToxoplasmosis, OcularWartsHumansToxoplasmaTrimethoprim, Sulfamethoxazole Drug CombinationTrimethoprim, Sulfamethoxazole Drug CombinationCXCR4Genetic ImmunodeficiencyOptic neuritisRetinitisToxoplasma gondiiTreatment

Identifiers

PMID31249677
PMCPMC6587139
OpenAlexW2908227914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.