Evidence map›Paper›PMID 31249649›Full record

ArticleOxidative medicine and cellular longevity2019

Mangiferin Attenuates Myocardial Ischemia-Reperfusion Injury via MAPK/Nrf-2/HO-1/NF-

Kun Liu, Fei Wang, Shuo Wang, Wei-Nan Li, Qing Ye

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cardioprotective effects of sinomenine in myocardial ischemia/reperfusion injury in a rat model.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
  9. Mechanism of Action of Flavonoids ofMolecules (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. D-Limonene mitigate myocardial injury in rats through MAPK/ERK/NF-κB pathway inhibition.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kun LiuDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Fei WangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Shuo WangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Wei-Nan LiDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Qing YeDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, China.ORCID 0000-0001-6874-5146
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the cardioprotective effect of mangiferin (MAF)

Indexed as

AnimalsCardiotonic AgentsGene Expression RegulationHeme Oxygenase (Decyclizing)In Vitro TechniquesMaleMitogen-Activated Protein Kinase 1Myocardial Reperfusion InjuryNF-E2-Related Factor 2NF-kappa BRatsRats, Sprague-DawleyXanthonesCardiotonic AgentsHeme Oxygenase (Decyclizing)Hmox1 protein, ratmangiferinMapk1 protein, ratMitogen-Activated Protein Kinase 1Nfe2l2 protein, ratNF-E2-Related Factor 2NF-kappa BXanthones

Identifiers

PMID31249649
PMCPMC6535818
OpenAlexW2945717815

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.