Trial reportPain research & management2019
Nonclosure of the Peritoneum during Appendectomy May Cause Less Postoperative Pain: A Randomized, Double-Blind Study.
Trial report in Pain research & management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02803463 (Peritoneal Closure Versus Non Closure During Open Appendectomy), which is not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Peritoneal Closure Versus Non Closure During Open Appendectomy: a Randomized Trial
Who cites it
3 citing papers in PubMed.
- Effect of peritoneal non-closure and closure during open appendectomy on post-operative pain: a randomized, double-blinded study.Langenbeck's archives of surgery · 2025Trial
- Perioperative factors influencing post-appendectomy outcomes in adults: a single-center prospective study in the North of Palestine.BMC surgery · 2025Observational
- No closure of the linea alba cervicalis reduces complications in endoscopic thyroidectomy.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We aim to evaluate the effect of peritoneal closure on postoperative pain and life quality associated with open appendectomy operations. Methods: This is a single-center, prospective, randomized, and double-blinded study. Here, 18-65-year-old patients who underwent open appendectomy for acute appendicitis were included. Demographic data of the patients, operation time, length of hospital stay, pain scores using a 10 cm visual analogue scale (VAS) on the first postoperative day, quality of life assessment using the EuroQol-5D-5L questionnaire on postoperative 10th day, deep wound dehiscence, bowel obstruction, and mortality data were recorded. Results: In total, 112 patients were included in the study. The demographic data showed no significant difference between the groups. The median VAS score was lower in the group with open peritoneum, but this difference was not statistically significant (3 vs. 4, Conclusion: Nonclosure of the peritoneum seems to shorten the duration of surgery without increasing complications during open appendectomy. Postoperative pain and life quality measures were not affected by nonclosure of the peritoneum. This trial is registered with NCT02803463.
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