Evidence map›Paper›PMID 31249636›Full record

SynthesisPain research & management2019

Quality of Life in Painful Peripheral Neuropathies: A Systematic Review.

Ayesha Girach, Thomas Henry Julian, Giustino Varrassi, Antonella Paladini, Athina Vadalouka, Panagiotis Zis

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Pain research & management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07160270 (Neuropathy in Waldenström's Macroglobulinemia), which is not on this map. Cited by 80 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 8 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07160270 recruitingnot on this mapstarted 2025, after this paper: background citation

Neuropathy in Waldenström's Macroglobulinemia: Pathophysiology, Prognosis and Treatment

Typeobservational_patient_registrySponsorRigshospitalet, DenmarkRan2025 to 2025Enrolled90ConditionsWaldenstrom Macroglobulinaemia, Peripheral Neuropathies
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 8 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Pooled it
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  17. The Role of Novel Biomarkers in the Early Management of Peripheral Diabetic Neuropathy.Central nervous system agents in medicinal chemistry · 2026
    Review
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Ayesha GirachThe Medical School, University of Sheffield, Sheffield, UK.
Thomas Henry JulianThe Medical School, University of Sheffield, Sheffield, UK.
Giustino VarrassiPaolo Procacci Foundation, Via Tacito 7, Roma, Italy.ORCID 0000-0002-3822-2923
Antonella PaladiniDepartment of MESVA, University of L'Aquila, L'Aquila, Italy.
Athina VadaloukaAthens Medical Centre, Athens, Greece.
Panagiotis ZisMedical School, University of Cyprus, Nicosia, Cyprus.ORCID 0000-0001-8567-3092
University of Sheffield · GBAthens Medical Center · GRFondazione Roma · ITUniversity of Cyprus · CYUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Neuropathic pain is a common presenting complaint of patients with peripheral neuropathy (PN) and is considered one of the most disabling neuropathic symptoms, with detrimental effects on patients' quality of life (QoL). The aim of this review was to overview the current literature that focuses on QoL in painful PN of various aetiologies. We sought to clarify the direct effect of pain and its treatment on patients' QoL. Methodology: A systematic computer-based literature search was conducted using the PubMed database to search for papers on QoL in painful PN. Information was extracted regarding prevalence, demographics, and response to treatment where relevant. Results: We identified 66 articles eligible for inclusion. The vast majority of studies ( Conclusion: The findings demonstrate that QoL is impaired in painful PN and should not be neglected in clinical practice. Patients' pain management and subsequent impact on QoL should routinely be assessed and monitored.

Indexed as

Quality of LifeHumansNeuralgiaPain Management

Identifiers

PMID31249636
PMCPMC6556282
OpenAlexW2944890330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.