ArticleFrontiers in cellular neuroscience2019
Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures.
Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2.Journal of cell science · 2025Article
- Epigenetic regulation of beta-endorphin synthesis in hypothalamic arcuate nucleus neurons modulates neuropathic pain in a rodent pain model.Nature communications · 2023Article
- Spinophilin-dependent regulation of GluN2B-containing NMDAR-dependent calcium influx, GluN2B surface expression, and cleaved caspase expression.Synapse (New York, N.Y.) · 2023Article
- Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations.Molecular neurobiology · 2022Article
- An N-terminal fusion allele to study melanin concentrating hormone receptor 1.Genesis (New York, N.Y. : 2000) · 2021Article
- Artificial Intelligence Approaches to Assessing Primary Cilia.Journal of visualized experiments : JoVE · 2021Article
- Cilia signaling and obesity.Seminars in cell & developmental biology · 2021Review
- Signaling in the primary cilium through the lens of the Hedgehog pathway.Wiley interdisciplinary reviews. Developmental biology · 2020Review
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Primary cilia dysfunction has been associated with hyperphagia and obesity in both ciliopathy patients and mouse models of cilia perturbation. Neurons throughout the brain possess these solitary cellular appendages, including in the feeding centers of the hypothalamus. Several cell biology questions associated with primary neuronal cilia signaling are challenging to address
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.