Evidence map›Paper›PMID 31249509›Full record

ArticleFrontiers in molecular neuroscience2019

Accelerated Age-Related Degradation of the Tectorial Membrane in the

Richard J Goodyear, Mary Ann Cheatham, Souvik Naskar, Yingjie Zhou, Richard T Osgood, Jing Zheng, Guy P Richardson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

  1. TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non-Syndromic Hearing Loss.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. ThemedRxiv : the preprint server for health sciences · 2025
    Article
  3. [The cochlear extracellular matrix gene mutations and hearing loss].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Richard J GoodyearSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.
Mary Ann CheathamThe Knowles Hearing Center, Northwestern University, Evanston, IL, United States.
Souvik NaskarSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.
Yingjie ZhouRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States.
Richard T OsgoodSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.
Jing ZhengThe Knowles Hearing Center, Northwestern University, Evanston, IL, United States.
Guy P RichardsonSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.
University of Sussex · GBNorthwestern University · USKnowles (United States) · US

Funding

STUDIES IN COCHLEAR HAIR CELL TRANSDUCTIONR01DC000089 · NIDCD · NORTHWESTERN UNIVERSITY · PI CHEATHAM, MARY ANN · 1989 to 2015
$10.1M
DYNAMIC INTERATION AMONG PROTEINS IN HAIR CELLSR01DC011813 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHENG, JING · 2012 to 2016
$1.6M
Dynamic interaction among proteins in hair cellsR56DC011813 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHENG, JING · 2017 to 2017
$490k
NIDCD NIH HHS R01 DC000089NIDCD NIH HHS R01 DC011813NIDCD NIH HHS R56 DC011813Wellcome Trust
6 · The paper itself

Abstract

CEACAM16 is a non-collagenous protein of the tectorial membrane, an extracellular structure of the cochlea essential for normal hearing. Dominant and recessive mutations in

Indexed as

CEACAM16cochleadeafnesshearingspontaneous otoacoustic emissionstectorial membrane

Identifiers

PMID31249509
PMCPMC6582249
OpenAlexW2949148647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.