ArticleFrontiers in neuroscience2019
A Protocol to Evaluate Retinal Vascular Response Using Optical Coherence Tomography Angiography.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- OCTA Signal Quality Augmentation Using the Isometric Handgrip Test to Maximize Vascular Flow (SQUEEZE): A Randomized Crossover Trial.Translational vision science & technology · 2024Trial
- Association Between Intraocular Pressure Changes and Optic Nerve Head and Macular Perfusion Parameters During Isometric Exercise: OCTA Study.Diagnostics (Basel, Switzerland) · 2026Article
- Localising OCTA changes induced by the isometric hand-grip test to the superficial retina in neovascular age-related macular degeneration.Eye and vision (London, England) · 2025Article
- Association of hemispheric retinal oxygen extraction and macular plexus-specific capillary density in moderate to advanced glaucomatous hemifield defect.Scientific reports · 2025Article
- Non-Invasive Retinal Vessel Analysis as a Predictor for Cardiovascular Disease.Journal of personalized medicine · 2024Review
- Retinal vascular reactivity in carriers of X-linked inherited retinal disease - a study using optical coherence tomography angiography.Frontiers in ophthalmology · 2024Article
- Patterns of Structural Changes in the Fundus Measured by Optical Coherence Tomography Angiography as Potential Markers of Acute Mountain Sickness.Translational vision science & technology · 2023Article
- Functional optical coherence tomography at altitude: retinal microvascular perfusion and retinal thickness at 3,800 meters.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Compensatory contribution of retinal larger vessels to perfusion density in diabetics without retinopathy.Scientific reports · 2022Article
- Methods to measure blood flow and vascular reactivity in the retina.Frontiers in medicine · 2022Review
- Normal tension glaucoma: A dynamic optical coherence tomography angiography study.Frontiers in medicine · 2022Article
- Retinal Microvascular Reactivity in Chronic Cigarette Smokers and Non-smokers: An Observational Cross-Sectional Study.Frontiers in medicine · 2021Article
- Retinal Vascular Reactivity in Type 1 Diabetes Patients Without Retinopathy Using Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2020Article
- Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy.Journal of clinical medicine · 2020Review
- Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography.Journal of visualized experiments : JoVE · 2020Article
- Evaluation of Foveal and Parafoveal Microvascular Changes Using Optical Coherence Tomography Angiography in Type 2 Diabetes Patients without Clinical Diabetic Retinopathy in South Korea.Journal of diabetes research · 2020Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOptical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and vasoconstriction retinal vascular responses with the available OCT-A technology.
methodsA commercial OCT-A device was used (AngioVue
resultsTwenty-four eyes of 24 healthy subjects (10 male) were studied. Mean age was 31.8 ± 8.2 years (range, 18-57 years). Mean parafoveal vessel density in the superficial plexus increased from 54.7 ± 2.6 in baseline conditions to 56.0 ± 2.0 in hypoxia ( DISCUSSION: In this work, we detail a simple, non-invasive, safe, and non-costly protocol to assess a central nervous system vascular response (i.e., the retinal circulation) using OCT-A technology. A vasodilatory response and a vasoconstriction response were observed in two physiologic conditions-mild hypoxia and isometric exercise, respectively. This protocol constitutes a new way of studying retinal vascular changes that may be applied in health and disease of multiple medical fields.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.