Refractory Insomnia in an Adolescent with Total Blindness.

Andrew S Tubbs, Michael A Grandner, Daniel Combs

Open access · greenAbstract readCase Reports

In one paragraph

Article in The Yale journal of biology and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 75% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

Exploring Sleep Challenges and Interventions in Children with a Vision Impairment: A Scoping Review.Children (Basel, Switzerland) · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew S TubbsSleep and Health Research Program, Department of Psychiatry, University of Arizona, Tucson, AZ.

Michael A GrandnerSleep and Health Research Program, Department of Psychiatry, University of Arizona, Tucson, AZ.

Daniel CombsDepartment of Pediatrics, University of Arizona, Tucson, AZ.

University of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a totally blind adolescent with refractory insomnia due to a combination of Non-24 hour sleep-wake disorder and restless leg syndrome that was successfully treated with tasimelteon, iron replacement, and gabapentin. To our knowledge, this is the first published report of treatment of N24 with tasimelteon in an adolescent. In addition, this case highlights the importance of recognizing and treating multifactorial causes of insomnia.

Indexed as

AdolescentBenzofuransBlindnessCyclopropanesDrug ResistanceDrug Therapy, CombinationFemaleGabapentinHumansIronRestless Legs SyndromeSleep Disorders, Circadian RhythmSleep Initiation and Maintenance DisordersBenzofuransCyclopropanesGabapentinIrontasimelteonadolescentinsomnianon-24 hour sleep-wake disordertasimelteon

Identifiers

PMID31249480

PMCPMC6585511

OpenAlexW3005907908

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.