Evidence map›Paper›PMID 31249472›Full record

ArticleMediators of inflammation2019

Characterization of Microbiota in Endometrial Fluid and Vaginal Secretions in Infertile Women with Repeated Implantation Failure.

Kotaro Kitaya, Yoko Nagai, Wataru Arai, Yoshiyuki Sakuraba, Tomomoto Ishikawa

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. The Role of Genital Tract Microbiome in Fertility: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  3. Trial
  4. Review
  5. Review
  6. Presence and Dominance ofDiseases (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Role of CD138Biomedicines · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kotaro KitayaReproduction Clinic Osaka, Grand Front Osaka Tower A 15F, 4-20 Oofuka-cho, Kita-ku, Osaka, 530-0011, Japan.ORCID 0000-0002-5693-3139
Yoko NagaiVarinos Inc., Dai 2 Gotanda Fujikoshi Bldg. 6F, 5-23-1 Higashigotanda, Shinagawa-ku, Tokyo, 141-0022, Japan.
Wataru AraiVarinos Inc., Dai 2 Gotanda Fujikoshi Bldg. 6F, 5-23-1 Higashigotanda, Shinagawa-ku, Tokyo, 141-0022, Japan.
Yoshiyuki SakurabaVarinos Inc., Dai 2 Gotanda Fujikoshi Bldg. 6F, 5-23-1 Higashigotanda, Shinagawa-ku, Tokyo, 141-0022, Japan.
Tomomoto IshikawaReproduction Clinic Osaka, Grand Front Osaka Tower A 15F, 4-20 Oofuka-cho, Kita-ku, Osaka, 530-0011, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies suggest that persisting intrauterine bacterial infectious conditions such as chronic endometritis potentially impair the embryo implantation process. The microbial environment in the female reproductive tract, however, remains largely undetermined in infertile patients with a history of repeated implantation failure (RIF). Using next-generation sequencing, we aimed to characterize the microbiota in the endometrial fluid (EF) and vaginal secretions (VS) in women with RIF. Twenty-eight infertile women with a history of RIF and eighteen infertile women undergoing the first

Indexed as

Embryo ImplantationAdultBurkholderiaEndometriumFemaleFertilization in VitroHumansInfertility, FemalePregnancyRNA, Ribosomal, 16SVaginaRNA, Ribosomal, 16S

Identifiers

PMID31249472
PMCPMC6556345
OpenAlexW2945742147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.