Evidence map›Paper›PMID 31249363›Full record

ArticleScientific reports2019

Pulmonary rehabilitation improves survival in patients with idiopathic pulmonary fibrosis undergoing lung transplantation.

Juliessa Florian, Guilherme Watte, Paulo José Zimermann Teixeira, Stephan Altmayer, Sadi Marcelo Schio, Letícia Beatriz Sanchez, Douglas Zaione Nascimento, Spencer Marcantonio Camargo, Fabiola Adélia Perin, José de Jesus Camargo and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04946708 (Using Technology to Engage Patients With Interstitial Lung Disease), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04946708 nacompletednot on this mapstarted 2021, after this paper: background citation

Using Technology to Engage Patients With Interstitial Lung Disease (ILD) in a Home a Home Exercise Program.

TypeinterventionalSponsorUniversity of ManitobaRan2021 to 2022Enrolled14ConditionsInterstitial Lung DiseaseArmsExercise program (virtual/remote)
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Exercise training for lung transplant candidates and recipients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Lung Transplant Rehabilitation-A Review.Life (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Antifibrotic therapy in idiopathic pulmonary fibrosis candidates for lung transplantation undergoing pulmonary rehabilitation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Observational
  14. Ambulatory oxygen therapy in lung transplantation candidates with idiopathic pulmonary fibrosis referred for pulmonary rehabilitation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  15. European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Frailty and aging-associated syndromes in lung transplant candidates and recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Juliessa FlorianPostgraduate Program in Pulmonology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Guilherme WatteDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil. g.watte@gmail.com.
Paulo José Zimermann TeixeiraPulmonary Rehabilitation Program, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Stephan AltmayerMedical Imaging Research Laboratory, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Sadi Marcelo SchioDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Letícia Beatriz SanchezDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Douglas Zaione NascimentoDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Spencer Marcantonio CamargoDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
Fabiola Adélia PerinDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
José de Jesus CamargoDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
José Carlos FelicettiDepartment of Lung Transplantation, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
José da Silva MoreiraPostgraduate Program in Pulmonology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Santa Casa de Misericórdia de Marília · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to evaluate whether a pulmonary rehabilitation program (PRP) is independently associated with survival in patients with idiopathic pulmonary fibrosis (IPF) undergoing lung transplant (LTx). This quasi-experimental study included 89 patients who underwent LTx due to IPF. Thirty-two completed all 36 sessions in a PRP while on the waiting list for LTx (PRP group), and 53 completed fewer than 36 sessions (controls). Survival after LTx was the main outcome; invasive mechanical ventilation (IMV), length of stay (LOS) in intensive care unit (ICU) and in hospital were secondary outcomes. Kaplan-Meier curves and Cox regression models were used in survival analyses. Cox regression models showed that the PRP group had a reduced 54.0% (hazard ratio = 0.464, 95% confidence interval 0.222-0.970, p = 0.041) risk of death. A lower number of patients in the PRP group required IMV for more than 24 hours after LTx (9.0% vs. 41.6% p = 0.001). This group also spent a mean of 5 days less in the ICU (p = 0.004) and 5 days less in hospital (p = 0.046). In conclusion, PRP PRP completion halved the risk of cumulative mortality in patients with IPF undergoing unilateral LTx.

Indexed as

Lung TransplantationAdultAgedFemaleHumansIdiopathic Pulmonary FibrosisKaplan-Meier EstimateMaleMiddle AgedPerioperative CarePrognosisRecovery of FunctionRehabilitationRespiration, ArtificialRespiratory Function TestsRetrospective Studies

Identifiers

PMID31249363
PMCPMC6597536
OpenAlexW2955275234

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.