Evidence map›Paper›PMID 31249342›Full record

ArticleScientific reports2019

NFATc3 controls tumour growth by regulating proliferation and migration of human astroglioma cells.

Katia Urso, Andrés Fernández, Patricia Velasco, Javier Cotrina, Belén de Andrés, Pilar Sánchez-Gómez, Aurelio Hernández-Laín, Sonsoles Hortelano, Juan Miguel Redondo, Eva Cano

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. NFATC3 enhances osteosarcoma progression by increasing PD-L1 and CXCL2 levels.Medical oncology (Northwood, London, England) · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Calcium and Neural Stem Cell Proliferation.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
  15. Review
  16. Isoform-Selective NFAT Inhibitor: Potential Usefulness and Development.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Epigenetics insights · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Katia UrsoDepartment of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Andrés FernándezChronic Disease Programme, Madrid, Spain. andres.fernandez@isciii.es.
Patricia VelascoChronic Disease Programme, Madrid, Spain.
Javier CotrinaChronic Disease Programme, Madrid, Spain.
Belén de AndrésCentro Nacional de Microbiología, Madrid, Spain.
Pilar Sánchez-GómezChronic Disease Programme, Madrid, Spain.ORCID http://orcid.org/0000-0002-0709-4973
Aurelio Hernández-LaínHospital Doce de Octubre, Madrid, Spain.
Sonsoles HortelanoInstituto de Enfermedades Raras, Instituto de Salud Carlos III, Madrid, Spain.
Juan Miguel RedondoDepartment of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.ORCID http://orcid.org/0000-0001-5779-9122
Eva CanoChronic Disease Programme, Madrid, Spain. ecano@isciii.es.ORCID http://orcid.org/0000-0003-2750-6135
Unidad Funcional de Investigación de Enfermedades Crónicas · ESSpanish National Centre for Cardiovascular Research · ESCentro Nacional de Microbiologia · ESHospital Fernández · ARHospital Universitario 12 De Octubre · ESInstituto de Salud Carlos III · ESUnidades Centrales Científico-Técnicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium/Calcineurin/Nuclear Factor of Activated T cells (Ca/CN/NFAT) signalling pathway is the main calcium (Ca

Indexed as

AnimalsAstrocytomaBiomarkersCell Line, TumorCell MembraneCell MovementCell ProliferationDisease Models, AnimalGene ExpressionGene Expression Regulation, NeoplasticGene SilencingHeterograftsHumansMiceMuscle ProteinsNFATC Transcription FactorsBiomarkersMuscle ProteinsNFATC3 protein, humanNFATC Transcription Factors

Identifiers

PMID31249342
PMCPMC6597574
OpenAlexW2954334516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.