Evidence map›Paper›PMID 31249340›Full record

ArticleScientific reports2019

Skin Carotenoid Index in a large Japanese population sample.

Akira Obana, Yuko Gohto, Werner Gellermann, Igor V Ermakov, Hiroyuki Sasano, Takahiko Seto, Paul S Bernstein

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

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  9. An Evaluation ofNutrients · 2024
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  16. Evaluation of native canine skin color by smartphone-based dermatoscopy.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Akira ObanaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, 1-12-12 Sumiyoshi, Naka-ku, Hamamatsu City, Shizuoka, 430-8558, Japan. obana@sis.seirei.or.jp.
Yuko GohtoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, 1-12-12 Sumiyoshi, Naka-ku, Hamamatsu City, Shizuoka, 430-8558, Japan.
Werner GellermannLongevity Link Corporation, Salt Lake City, UT, United States of America.
Igor V ErmakovLongevity Link Corporation, Salt Lake City, UT, United States of America.
Hiroyuki SasanoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, 1-12-12 Sumiyoshi, Naka-ku, Hamamatsu City, Shizuoka, 430-8558, Japan.
Takahiko SetoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, 1-12-12 Sumiyoshi, Naka-ku, Hamamatsu City, Shizuoka, 430-8558, Japan.
Paul S BernsteinDepartment of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.ORCID http://orcid.org/0000-0002-4228-7666
Seirei Hamamatsu General Hospital · JPLongevity Biotech (United States) · USHamamatsu Photonics (Japan) · JPUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.

Indexed as

AdolescentAdultAgedAged, 80 and overCarotenoidsDatabases, FactualFemaleHumansJapanMaleMiddle AgedSkinYoung AdultCarotenoids

Identifiers

PMID31249340
PMCPMC6597710
OpenAlexW2954797199

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.