Evidence map›Paper›PMID 31248985›Full record

ArticleThe Journal of biological chemistry2019

Ca

Xin Liang, Damien S K Samways, Jane Cox, Terrance M Egan

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Xin LiangSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University, Guangzhou 510275, China.
Damien S K SamwaysDepartment of Biology, Clarkson University, Potsdam, New York 13699.
Jane CoxDepartment of Pharmacology and Physiology and The Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Terrance M EganDepartment of Pharmacology and Physiology and The Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri 63104. Electronic address: terrance.egan@health.slu.edu.
Saint Louis University · USClarkson University · USSun Yat-sen University · CN

Funding

Selective regulation of the calcium component of the ATP-gated P2X7 currentR01GM112188 · NIGMS · SAINT LOUIS UNIVERSITY · PI EGAN, TERRANCE M · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM112188
6 · The paper itself

Abstract

Activation of ionotropic P2X receptors increases free intracellular Ca

Indexed as

Alternative SplicingCalcium SignalingAmino Acid SubstitutionCalciumHEK293 CellsHumansMutagenesis, Site-DirectedMutation, MissenseProtein DomainsProtein IsoformsReceptors, Purinergic P2X7CalciumP2RX7 protein, humanProtein IsoformsReceptors, Purinergic P2X7calcium channelcalcium transportfractional calcium currention channelligand-gatedP2X 7 (P2X7) P2RX7patch clamppatch-clamp fluorometrypermeabilitypurinergic receptorsplice variant

Identifiers

PMID31248985
PMCPMC6699846
OpenAlexW2954705763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.