ArticleAJNR. American journal of neuroradiology2019
Diagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal Enhancement.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06349603 (Integrated Physiotherapy Approach for Susac Syndrome), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Integrated Physiotherapy Approach for Susac Syndrome: A Comprehensive Case Study
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical Characterization and Ancillary Tests in Susac Syndrome: A Systematic Review.Neurology(R) neuroimmunology & neuroinflammation · 2024Pooled it
- Leptomeningeal enhancement in multiple sclerosis and other neurological diseases: A systematic review and Meta-Analysis.NeuroImage. Clinical · 2022Pooled it
- CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review.NeuroImage. Clinical · 2020Pooled it
- Endothelial Cell Proteins as Biomarkers in Susac Syndrome.Annals of clinical and translational neurology · 2026Article
- Fluorescein Angiography as a Surrogate Marker of Disease Activity in Susac Syndrome.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Imaging of brain barrier inflammation and brain fluid drainage in human neurological diseases.Cellular and molecular life sciences : CMLS · 2024Review
- Case report: Susac syndrome-two ends of the spectrum, single center case reports and review of the literature.Frontiers in neurology · 2024Article
- Meningeal inflammation as a driver of cortical grey matter pathology and clinical progression in multiple sclerosis.Nature reviews. Neurology · 2023Review
- Leptomeningeal Interfoliar Enhancement on Vessel Wall MR Imaging as a Unique Radiologic Finding of Susac Syndrome.AJNR. American journal of neuroradiology · 2023Article
- Case report: 3D intracranial vessel wall MRI in Susac syndrome: potential relevance for diagnosis and therapeutic management.Frontiers in neurology · 2023Article
- Autoimmune disease of head and neck, imaging, and clinical review.The neuroradiology journal · 2022Review
- Diagnosis, differential diagnosis and misdiagnosis of Susac syndrome.European journal of neurology · 2022Article
- Autoimmune diseases of the brain, imaging and clinical review.The neuroradiology journal · 2022Review
- Neurologic Involvement of Patients with Coronavirus Disease 2019: Making the Most of MRI.Radiology · 2020Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeLeptomeningeal enhancement can be found in a variety of neurologic diseases such as Susac Syndrome. Our aim was to assess its prevalence and significance of leptomeningeal enhancement in Susac syndrome using 3T postcontrast fluid-attenuated inversion recovery MR imaging. MATERIALS AND
methodsFrom January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs (5.9 MRIs is the mean number per patient over a median period of 46 months) of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Fisher tests were used to compare the 2 groups, and mixed-effects logistic models were used for analysis of clinical and imaging follow-up of patients with Susac syndrome.
resultsPatients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group (
conclusionsLeptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and in predicting clinical relapse.
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