Evidence map›Paper›PMID 31248860›Full record

ArticleAJNR. American journal of neuroradiology2019

Extent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular Subtype.

S H Patel, A G Bansal, E B Young, P P Batchala, J T Patrie, M B Lopes, R Jain, C E Fadul, D Schiff

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

S H PatelFrom the Departments of Radiology and Medical Imaging (S.H.P., A.G.B., E.B.Y., P.P.B.) shp4k@virginia.edu.ORCID 0000-0002-9739-4362
A G BansalFrom the Departments of Radiology and Medical Imaging (S.H.P., A.G.B., E.B.Y., P.P.B.).ORCID 0000-0001-8276-8416
E B YoungFrom the Departments of Radiology and Medical Imaging (S.H.P., A.G.B., E.B.Y., P.P.B.).ORCID 0000-0002-3649-9048
P P BatchalaFrom the Departments of Radiology and Medical Imaging (S.H.P., A.G.B., E.B.Y., P.P.B.).ORCID 0000-0002-3744-7012
J T PatriePublic Health Sciences (J.T.P.).ORCID 0000-0001-7392-830X
M B LopesPathology (M.B.L.), Divisions of Neuropathology and Molecular Diagnostics.ORCID 0000-0001-8661-6727
R JainDepartments of Radiology (R.J.).ORCID 0000-0002-4879-0457
C E FadulDivision of Neuro-Oncology (C.E.F., D.S.), University of Virginia Health System, Charlottesville, Virginia.ORCID 0000-0001-7459-7661
D SchiffDivision of Neuro-Oncology (C.E.F., D.S.), University of Virginia Health System, Charlottesville, Virginia.ORCID 0000-0002-1896-2502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDiffuse lower-grade gliomas are classified into prognostically meaningful molecular subtypes. We aimed to determine the impact of surgical resection on overall survival in lower-grade glioma molecular subtypes. MATERIALS AND

methodsFor 172 patients with lower-grade gliomas (World Health Organization grade II or III), pre- and postsurgical glioma volumes were determined using a semiautomated segmentation software based on FLAIR or T2-weighted MR imaging sequences. The association of pre- and postsurgical glioma volume and the percentage of glioma resection with overall survival was determined for the entire cohort and separately for lower-grade glioma molecular subtypes based on

resultsFor the entire cohort, postsurgical glioma volume (hazard ratio, 1.80; 95% CI, 1.18-2.75;

conclusionsThe extent of surgical resection has a differential survival impact in patients with lower-grade gliomas based on their molecular subtype.

Indexed as

AdultBrain NeoplasmsFemaleGliomaHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedMutationPrognosisRetrospective StudiesIsocitrate Dehydrogenase

Identifiers

PMID31248860
PMCPMC7048539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.