Evidence map›Paper›PMID 31248675›Full record

ArticleAnnals of emergency medicine2020

The Association of Physician Orders for Life-Sustaining Treatment With Intensity of Treatment Among Patients Presenting to the Emergency Department.

Kelly C Vranas, Amber L Lin, Dana Zive, Susan W Tolle, Scott D Halpern, Christopher G Slatore, Craig Newgard, Robert Y Lee, Erin K Kross, Donald R Sullivan

Open access · greenAbstract read
In one paragraph

Article in Annals of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. [S1 guideline on sustainability in intensive care and emergency medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Review
  5. Article
  6. An Integrative Review of the State of POLST Science: What Do We Know and Where Do We Go?Journal of the American Medical Directors Association · 2024
    Review
  7. Article
  8. Article
  9. "Don't Talk to Them About Goals of Care": Understanding Disparities in Advance Care Planning.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kelly C VranasDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research and Development, VA Portland Health Care System, Portland, OR; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address: vranas@ohsu.edu.
Amber L LinCenter for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health & Science University, Portland, OR.
Dana ZiveCenter for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health & Science University, Portland, OR.
Susan W TolleDivision of General Internal Medicine and Geriatrics, and Center for Ethics in Health Care, Oregon Health & Science University, Portland, OR.
Scott D HalpernPalliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Christopher G SlatoreDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research and Development, VA Portland Health Care System, Portland, OR.
Craig NewgardCenter for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health & Science University, Portland, OR.
Robert Y LeeCambia Palliative Care Center of Excellence and the Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA.
Erin K KrossCambia Palliative Care Center of Excellence and the Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA.
Donald R SullivanDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research and Development, VA Portland Health Care System, Portland, OR.
Oregon Health & Science University · USUniversity of Washington · USUniversity of Pennsylvania · US

Funding

Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3M
Oregon Multidisciplinary Training Program in Emergency Medicine Clinical ResearchK12HL108974 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NEWGARD, CRAIG D. · 2011 to 2015
$3.8M
Palliative Care Research Training GrantT32HL125195 · NHLBI · UNIVERSITY OF WASHINGTON · PI KROSS, ERIN KATHRYN, SHARMA, RASHMI K. · 2015 to 2024
$3.2M
Oregon Emergency Care Research Multidisciplinary Training ProgramK12HL133115 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRIS, CYNTHIA D, NEWGARD, CRAIG D. · 2016 to 2020
$2.9M
University of Washington Implementation Science Training Program (UW-ISTP)K12K12HL137940 · NHLBI · UNIVERSITY OF WASHINGTON · PI AU, DAVID H, CURTIS, J RANDALL · 2017 to 2021
$2.9M
Impact of Specialist Palliative Care on Outcomes in Advanced Stage Lung CancerK07CA190706 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SULLIVAN, DONALD R · 2015 to 2019
$826k
Goal-discordant care in acute respiratory failure: risk factors and mechanismsF32HL142211 · NHLBI · UNIVERSITY OF WASHINGTON · PI LEE, ROBERT YING-FU · 2018 to 2019
$99k
NCI NIH HHS K07 CA190706NCI NIH HHS L30 CA179412NHLBI NIH HHS F32 HL142211NHLBI NIH HHS K12 HL108974NHLBI NIH HHS K12 HL133115NHLBI NIH HHS K12 HL137940NHLBI NIH HHS T32 HL083808NHLBI NIH HHS T32 HL125195
6 · The paper itself

Abstract

STUDY

objectivePhysician Orders for Life-Sustaining Treatment (POLST) forms are intended to help prevent the provision of unwanted medical interventions among patients with advanced illness or frailty who are approaching the end of life. We seek to evaluate how POLST form completion, treatment limitations, or both influence intensity of treatment among patients who present to the emergency department (ED).

methodsThis was a retrospective cohort study of adults who presented to the ED at an academic medical center in Oregon between April 2015 and October 2016. POLST form completion and treatment limitations were the main exposures. Primary outcome was hospital admission; secondary outcomes included ICU admission and a composite measure of aggressive treatment.

resultsA total of 26,128 patients were included; 1,769 (6.8%) had completed POLST forms. Among patients with POLST, 52.1% had full treatment orders, and 6.4% had their forms accessed before admission. POLST form completion was not associated with hospital admission (adjusted odds ratio [aOR]=0.97; 95% confidence interval [CI] 0.84 to 1.12), ICU admission (aOR=0.82; 95% CI 0.55 to 1.22), or aggressive treatment (aOR=1.06; 95% CI 0.75 to 1.51). Compared with POLST forms with full treatment orders, those with treatment limitations were not associated with hospital admission (aOR=1.12; 95% CI 0.92 to 1.37) or aggressive treatment (aOR=0.87; 95% CI 0.5 to 1.52), but were associated with lower odds of ICU admission (aOR=0.31; 95% CI 0.16 to 0.61).

conclusionAmong patients presenting to the ED with POLST, the majority of POLST forms had orders for full treatment and were not accessed by emergency providers. These findings may partially explain why we found no association of POLST with treatment intensity. However, treatment limitations on POLST forms were associated with reduced odds of ICU admission. Implementation and accessibility of POLST forms are crucial when considering their effect on the provision of treatment consistent with patients' preferences.

Indexed as

Advance DirectivesEmergency Service, HospitalPhysiciansAdultAgedComorbidityFemaleHumansMaleMiddle AgedOregonPatient AdmissionResuscitation OrdersRetrospective StudiesTerminal Care

Identifiers

PMID31248675
PMCPMC6928444
OpenAlexW2956059351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.