ArticleBMC veterinary research2019
Anthelmintic efficacy against gastrointestinal nematodes in goats raised under mountain farming conditions in northern Italy.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Anthelmintic Resistance in Livestock Farming: Challenges and Perceptions of Farmers and Veterinarians.Pathogens (Basel, Switzerland) · 2025Article
- Treatment ineffectiveness towards Haemonchus contortus is highly prevalent in sheep and goat farms of North-Eastern Italy.BMC veterinary research · 2024Article
- First Report of Benzimidazole Resistance in Field Population ofPathogens (Basel, Switzerland) · 2024Article
- Effect of Ivermectin on the Expression of P-Glycoprotein in Third-Stage Larvae ofAnimals : an open access journal from MDPI · 2023Article
- Awareness and control methods of gastrointestinal parasites of merino sheep among farmers from different agro-ecological zones of Lesotho.Veterinary world · 2021Article
- Multiple Anthelmintic Resistance at a Goat Farm in Slovakia.Helminthologia · 2021Article
- Resistance of strongylid nematodes to anthelmintic drugs and driving factors at Czech goat farms.BMC veterinary research · 2021Article
- High frequency of benzimidazole resistance alleles in trichostrongyloids from Austrian sheep flocks in an alpine transhumance management system.BMC veterinary research · 2020Article
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Authors and funding
4 authors.
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Abstract
backgroundThis study aimed to evaluate the efficacy of anthelmintics in goats raised under mountain farming conditions in northern Italy. On 8 goat farms (n = 143 animals), a faecal egg count reduction (FECR) test was done after farmers conducted their routine anthelmintic treatments. Furthermore, on 5 goat farms (n = 135 animals) a FECR test was done under controlled conditions applying oral formulations of a macrocyclic lactone (ML), benzimidazole (BZ) (partly in combination with salicylanilide (SA)) or a combination of imidazothiazole (IT) and SA on the same farm. AR was assumed if FECR and the upper confidence interval (CI) was < 95% and the lower 95% CI was < 90%.
resultsUnderdosing was found in 6 of the 8 farms tested after routine treatments. Out of the 6 routinely ML-treated goat flocks, only three were found where ML showed adequate efficacy. FECR in all others ranged between 64 and 93%. In one flock Trichostrongylus spp. and in one Haemonchus spp. larvae were identified after treatment. BZ-treated flocks had an efficacy of 99 and 37%. Larvae identified after treatment were Trichostrongylus spp. in one and Haemonchus spp. in the other flock. Under controlled conditions, ML had an adequate efficacy on 4 farms and a FECR of 88% on another one. BZ was effective on all farms. The combination of BZ and SA had a FECR of 99% on the farm it was tested. IT + SA in combination was effective on 2 farms and had a FECR of 91% on a third farm. Larvae identified after treatment were composed of Haemonchus spp. (ML and BZ), Trichostrongylus spp. (BZ) and Teladorsagia spp. (BZ and SA).
conclusionsThis first report on the prevalence of AR in goats in the mountainous region of South Tyrol reveals a low efficacy of the most commonly used anthelmintics after routine treatments. This might be explained by a high level of underdosing as observed in the farms. However, results from the controlled FECR tests suggest that the observed level of AR was lower but cannot be solely explained by underdosing.
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