ArticleCells2019
Circular RNA circ-FoxO3 Inhibits Myoblast Cells Differentiation.
Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Role of circular RNAs in preeclampsia (Review).Experimental and therapeutic medicine · 2024Review
- Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells <em>via</em> regulation of miR-1234/TP53I11 axis.European journal of histochemistry : EJH · 2022Article
- Circular RNAs in stem cells: from basic research to clinical implications.Bioscience reports · 2022Review
- Identification and characterization of circRNAs related to meat quality during embryonic development of the longissimus dorsi muscle in two pig breeds.Frontiers in genetics · 2022Article
- Characterization of lncRNA/circRNA-miRNA-mRNA network to reveal potential functional ceRNAs in the skeletal muscle of chicken.Frontiers in physiology · 2022Article
- Type 1 Diabetes Mellitus-Related circRNAs Regulate CD4+ T Cell Functions.BioMed research international · 2022Article
- Functions and mechanisms of circular RNAs in regulating stem cell differentiation.RNA biology · 2021Review
- CircRNA FUT10 regulates the regenerative potential of aged skeletal muscle stem cells by targeting HOXA9.Aging · 2021Article
- CircAgtpbp1 Acts as a Molecular Sponge of miR-543-5p to Regulate the Secretion of GH in Rat Pituitary Cells.Animals : an open access journal from MDPI · 2021Article
- Functional Non-coding RNA During Embryonic Myogenesis and Postnatal Muscle Development and Disease.Frontiers in cell and developmental biology · 2021Review
- The Emerging Roles of circFOXO3 in Cancer.Frontiers in cell and developmental biology · 2021Review
- Retraction: Li, X.; et al. Circular RNA circ-FoxO3 Inhibits Myoblast Cells Differentiation.Cells · 2020Article
- A Novel Nanobody Directed against Ovine Myostatin to Enhance Muscle Growth in Mouse.Animals : an open access journal from MDPI · 2020Article
- Article
- circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan.GeroScience · 2020Article
- Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells.Stem cells international · 2020Review
- Circular RNA SAMD4A controls adipogenesis in obesity through the miR-138-5p/EZH2 axis.Theranostics · 2020Article
Corrections and comments
- Retraction · 2020-11-19Duplication of/in Image ·
- Retracted
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CircRNA is a type of closed circular non-coding RNA formed by reverse splicing and plays an important role in regulating the growth and development of plants and animals. To investigate the function of circ-FoxO3 in mouse myoblast cells' (C2C12) differentiation and proliferation, we used RT-qPCR to detect the expression level of circ-FoxO3 in mouse myoblast cells at different densities and different differentiation stages, and the specific interference fragment was used to inhibit the expression level of circ-FoxO3 in myoblast cells to observe its effect on myoblast cells proliferation and differentiation. We found that the expression level of circ-FoxO3 in myoblast cells increased with the prolongation of myoblast cells differentiation time, and its expression level decreased with the proliferation of myoblast cells. At the same time, we found that the differentiation ability of the cells was significantly increased (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.