Evidence map›Paper›PMID 31248190›Full record

ArticleAnimals : an open access journal from MDPI2019

Arachidonic Acid Regulation of Intracellular Signaling Pathways and Target Gene Expression in Bovine Ovarian Granulosa Cells.

Nina Zhang, Liqiang Wang, Guoya Luo, Xiaorong Tang, Lizhu Ma, Yuxin Zheng, Shujie Liu, Christopher A Price, Zhongliang Jiang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Effects of DietaryAnimals : an open access journal from MDPI · 2026
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  19. Non-esterified fatty acids in the ovary: friends or foes?Reproductive biology and endocrinology : RB&E · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Nina ZhangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. ninazhang255@gmail.com.
Liqiang WangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. jhy12@126.com.
Guoya LuoCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. gagaluo23@163.com.
Xiaorong TangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. xiaortang@126.com.
Lizhu MaCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. malizhu@nwafu.edu.cn.
Yuxin ZhengCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. 18309256612@163.com.
Shujie LiuState Key Laboratory of Plateau Ecology and Agriculture, Key Laboratory of Plateau Grazing Animal Nutrition and Feed Science of Qinghai Province, Qinghai Plateau Yak Research Center, Qinhai University, Xining 810016, Qinghai, China. 13519705806@126.com.
Christopher A PriceCentre de recherche en reproduction fertility, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, QC J2S 7C6, Canada. christopher.price@umontreal.ca.
Zhongliang JiangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Xianyang 712100, Shaanxi, China. jiangzhongliang@nwsuaf.edu.cn.
Northwest A&F University · CNQinghai University · CNUniversité de Montréal · CA

Funding

National Key Research and Development Program 2016YFD0500500National Natural Science Foundation of China 31572406
6 · The paper itself

Abstract

In the present study, AA was used to challenge bovine ovarian granulosa cells in vitro and the related parameters of cellular and molecular biology were measured. The results indicated that lower doses of AA increased survival of bovine granulosa cells whereas higher doses of AA suppressed survival. While lower doses of AA induced accumulation of lipid droplet in granulosa cells, the higher dose of AA inhibited lipid accumulation, and AA increased abundance of

Indexed as

arachidonic acidcell survivalgranulosa cellslipid dropletsteroid hormone

Identifiers

PMID31248190
PMCPMC6617051
OpenAlexW2952165613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.